The 16 Best Luxury Hotels with Spa in South Carolina (2025)

Nestled along the serene banks of the May River, Montage Palmetto Bluff is a sumptuous retreat where Southern charm meets modern elegance. Imagine waking to the gentle rustle of Spanish moss in the trees and the soft lapping of water against the dock, inviting you to indulge in moments of pure tranquility and romance.

Total Relaxation - Unwind in the full-service spa, where soothing aromas of eucalyptus and lavender envelop you, perfect for wellness seekers craving rejuvenation amid picturesque surroundings.

Romantic Break - With intimate dining options like candlelit dinners at Jasmine Restaurant, savor exquisite local flavors while sharing stories under the twinkling stars—a setting crafted for unforgettable memories.

Outdoor Adventures - Venture out to explore scenic bike trails or embark on guided kayaking excursions across shimmering waters, immersing yourself in the region's natural beauty while creating cherished adventures.

Guest Experiences - After a long day of exploring, the scent of freshly made s'mores wafted through the air as guests gathered around the fire pits, laughter mixing with the sounds of nature—a perfect way to end the evening under the Southern sky.

Nestled in the heart of Charleston, Hotel Bennett is an exquisite sanctuary where historic charm meets modern elegance. As you step through its grand entrance, the gentle hum of laughter and clinking glasses from the rooftop bar mingles with the refreshing scent of blooming magnolias, creating an inviting atmosphere that beckons both romance and relaxation.

Total Relaxation - Indulge in serene moments by the glistening outdoor pool or unwind at the luxurious spa, where soft melodies and fragrant essential oils melt away the day's stresses, leaving you rejuvenated and refreshed.

Culinary Delights - Savor a culinary journey at Gabrielle’s, where each dish showcases local ingredients infused with American and French flair, tantalizing your taste buds with every bite while you enjoy stunning views of the cityscape.

Historic Charm - Experience the essence of Charleston as you wander through nearby historic streets, where cobblestones whisper tales of the past and vibrant local markets invite you to explore artisanal crafts and delightful cuisine.

Guest Experiences - Awakening to the aroma of freshly brewed coffee wafting from their room's high-end machine, guests relish those tranquil morning moments on their balcony overlooking the city, basking in the warmth of Southern hospitality and the vibrant sights below.

Nestled in the heart of historic Charleston, The Charleston Place envelops you in an atmosphere where Southern charm meets modern elegance. Picture yourself wandering through its stunning lobby, where the gentle notes of live piano music intertwine with the fragrant aroma of freshly brewed coffee, creating an inviting haven for relaxation and indulgence.

Romantic Break - With beautifully appointed rooms featuring sumptuous fabrics and plush furnishings, every corner of this hotel whispers romance, setting the stage for unforgettable moments with your loved one.

Spa breaks - The full-service spa beckons wellness enthusiasts with its serene ambiance, offering rejuvenating treatments that melt away stress, leaving you to bask in tranquility by the glistening saltwater pool.

City Style - Located just steps from the vibrant heart of Charleston, guests can wander through cobblestone streets lined with boutique shops and local markets, savoring delightful culinary experiences at every turn.

Guest Experiences - As you sink into a plush armchair in the elegant lobby, the soothing sounds of piano melodies blend effortlessly with the laughter of fellow travelers, while the enticing scent of Southern cuisine wafts through the air, inviting you to explore the culinary delights awaiting at Charleston Grill.

Nestled in the heart of Charleston, The Dewberry exudes an ambiance of understated luxury and Southern charm, wrapped in mid-20th century elegance. With its historic façade and meticulously curated interiors, this boutique hotel invites guests to indulge in a sanctuary where romance and sophistication intertwine amidst the vibrant pulse of city life.

Total relaxation - Recharge your spirit in the serene Spa at the Dewberry, where expert therapists envelop you in soothing scents and calming sounds, offering treatments that transport you far beyond the bustling streets of Charleston.

Romantic Break - Share intimate moments over artisanal meals at the American Southern brasserie, where the aroma of freshly baked bread mingles with the laughter of friends and the gentle clinking of glasses at twilight, creating an enchanting backdrop for romance.

City Style - Experience the chic vibrancy of Charleston through the hotel's floor-to-ceiling windows, where stunning views of Marion Square unfold and seamlessly blend the energy of local markets and culture right outside your door.

Guest Experiences - As I stepped into the lobby, the elegant scent of fresh flowers filled the air, perfectly complementing the plush textures of the decor. I marveled at the thoughtful details, like a clothes steamer waiting in my room—a small yet appreciated gesture that turned my travel-worn attire into something crisp and polished.

Nestled gracefully along the shimmering shores of Charleston Harbor, The Beach Club at Charleston Harbor Resort and Marina offers an intimate escape where coastal elegance meets modern luxury. With its sun-drenched terraces and serene ambiance, this chic haven invites couples and discerning travelers alike to indulge in unforgettable moments framed by breathtaking views of the iconic USS Yorktown.

Outstanding Location - Step outside your room and breathe in the salty sea air, as the gentle lapping of waves beckons you toward private beach access just a short trolley ride away. Explore the charming streets of nearby Sullivan's Island or relish the stunning sunsets casting an amber glow over the harbor.

Spa Breaks - Rejuvenate your senses in the tranquil spa, where the scent of essential oils fills the air as skilled therapists guide you through blissful treatments designed to melt your cares away. Whether it's a soothing massage or an invigorating facial, each experience is tailored to leave you feeling renewed.

Chic Dining - Savor culinary delights with a view at the waterfront Charleston Harbor Fish House, where the aroma of freshly caught seafood mingles with the sound of laughter from nearby tables. Enjoy open-air dining while watching boats glide across the water, making every meal an experience for the senses.

Guest Experiences - A guest recently shared their delight at discovering the poolside service's personalized touch; the refreshing scent of sunscreen mingled with the laughter of friends basking in the sun, creating a lively atmosphere that felt both vibrant and inviting. Another marveled at the soft, coastal decor of their room, reminiscent of a bright beach cottage, instantly wrapping them in a sense of calm.

Nestled along the pristine shores of Isle of Palms, Wild Dunes Resort - Sweetgrass Inn and Boardwalk Inn offers an elegant escape where Southern charm meets modern luxury. Imagine waking up to the soft murmur of ocean waves and the scent of salt in the air, as you prepare for a leisurely day filled with sun-drenched adventures and indulgent relaxation.

Beach Life - Just a heartbeat away from the golden sands, indulge in the sun-soaked beach life where each sunset paints the sky in hues of orange and purple, perfect for romantic strolls or serene moments of reflection.

Spa Breaks - Experience total rejuvenation at the on-site spa, where soothing scents of essential oils mingle in the air, inviting you to unwind with signature treatments that melt away tension and refresh your spirit.

Golf Getaway - Challenge yourself on two championship golf courses, where the gentle sea breeze and meticulously landscaped fairways create a golfer's paradise, welcoming both seasoned players and newcomers alike.

Guest Experiences - One guest described their delight at finding a cozy nook by the adults-only pool, the sound of laughter mingling with distant waves while they savored a cocktail; others relished the view from their room, where glimpses of the ocean peeked through lush palm fronds, painting a picture of tranquility.

Nestled along the pristine shores of Myrtle Beach, Marriott Myrtle Beach Resort & Spa at Grande Dunes offers a sanctuary where luxury meets relaxation. Picture waking up to gentle ocean breezes and the soothing sound of waves lapping at the shore, all while enjoying direct access to a private beach that feels like your own slice of paradise.

Spa Retreats - Indulge in holistic wellness at Hibiscus Spa, where the air is infused with calming scents as skilled therapists transport you to serenity through soothing massages and rejuvenating facials, creating a tranquil escape from the everyday hustle.

Beachfront Bliss - Step out onto the soft, warm sand from the beachfront outdoor pool and feel the sun envelop you; it’s a perfect setting for lazy days spent lounging under colorful umbrellas or splashing playfully in the surf.

Culinary Delights - Savor exquisite flavors at any of the three onsite restaurants, where local ingredients shine; whether it's a romantic dinner by candlelight or a casual cocktail at The Bar, each meal becomes a memorable experience filled with enticing aromas and delightful tastes.

Guest Experiences - Guests often mention the welcoming warmth of the staff, recalling how a bellboy went out of his way to share tips about hidden local gems, while others cherished the peaceful ambiance that allowed them to relax fully—just moments away from a vibrant beach filled with laughter.

Nestled within the exclusive Palmetto Dunes community, the Omni Hilton Head Oceanfront Resort is an oasis of elegance and tranquility that beckons you to lose yourself in its serene beauty. With soft ocean breezes and a private stretch of golden beach, this luxurious retreat offers couples a romantic escape where every detail whispers indulgence and relaxation.

Romantic Getaway - Embrace intimacy with endless ocean views from your private balcony, where the gentle sound of waves serves as the backdrop for candlelit evenings under the stars.

Spa Retreat - Immerse yourself in rejuvenation at the on-site spa, where soothing aromas of exotic oils blend with the tranquil sounds of nature to create an atmosphere of pure bliss—perfect for wellness enthusiasts seeking serenity.

Active Adventures - For those craving adventure, explore scenic bike paths that meander through lush landscapes or challenge friends to a spirited game on the nearby pickleball courts, all while enjoying the resort's chic coastal vibe.

Guest Experiences - Picture yourself at the adult pool, where attentive staff glide around with refreshing cocktails, their laughter mingling with the soft rustle of palm leaves—a moment of sheer relaxation amidst the tropical ambiance.

Nestled along the pristine shores of Hilton Head Island, Marriott's Barony Beach Club beckons you to experience a symphony of luxury and tranquility. Here, the soft whispers of ocean waves mingle with the warm South Carolina breeze, inviting couples and adventurers alike to indulge in a retreat that feels both intimate and expansive. The elegant design and thoughtful amenities create an atmosphere where every moment is a celebration of relaxation and romance.

Beach Life - Step onto the powdery sands just steps from your door, where the rhythm of the tide sets the perfect backdrop for sun-soaked afternoons and moonlit strolls. The beach invites you to unwind, whether you're lounging under a vibrant umbrella or savoring the salty sea air as you explore the shoreline.

Spa Breaks - Immerse yourself in pure rejuvenation at the on-site spa, where soothing aromas waft through the air, beckoning you to experience treatments designed to pamper your body and soul. After a day of indulgence, linger in the serene hot tub, allowing the gentle bubbles to wash away any remnants of stress.

Total Relaxation - Every accommodation is a haven of comfort, boasting spacious layouts filled with contemporary elegance. Imagine sipping your morning coffee while gazing at the ocean, the kitchen equipped with everything you need to create a delightful breakfast—your home away from home, elevated by the peaceful sounds of nature just outside your window.

Guest Experiences - Picture this: returning from a sun-drenched day to find your room impeccably clean and inviting, the scent of fresh linens enveloping you like a welcome embrace. One guest remarked on the joy of discovering a fully stocked kitchen, making family meals not just a necessity, but a cherished ritual—complete with laughter echoing through the open spaces.

Nestled along the pristine shores of Myrtle Beach, North Beach Resort & Villas is a luxurious sanctuary where elegance meets coastal charm. Picture yourself unwinding in lavish accommodations that exude comfort and style, all while the soothing sound of ocean waves dances in the background, creating the perfect backdrop for romance and relaxation.

Romantic Getaway - Indulge in intimate moments as you stroll hand-in-hand along the beautiful beachfront, where golden sands meet the azure waters—each sunset painting the sky with vibrant hues. The romantic ambiance is enhanced by candlelit dinners and quiet corners perfect for stolen whispers.

Total Relaxation - Revitalize your senses at Cinzia Spa, where the air is infused with calming essential oils and the soft sounds of flowing water create an oasis of tranquility. Experience rejuvenating massages or unwind in a whirlpool bath, enveloped in luxurious serenity.

Beach Life - Step outside to embrace the lively energy of beach life; feel the warm sun on your skin as you explore local markets and savor delectable bites from nearby eateries. The vibrant atmosphere invites adventure, whether you’re kayaking over gentle waves or discovering hidden gems amongst eclectic shops.

Guest Experiences - One guest remarked on the sheer delight of waking up to the scent of fresh sea air and the cheerful laughter of children splashing in the expansive water park—a constant reminder of the joy and liveliness that fills every corner of this vast property.

Nestled along the sun-kissed shores of Myrtle Beach, Royale Palms Condominiums exudes an aura of tranquility and romance. Here, the gentle sound of waves lapping against the shore harmonizes with the allure of chic accommodations, inviting guests to immerse themselves in luxury while relishing breathtaking ocean views from their private balconies.

Total Relaxation - Indulge in ultimate serenity at SPA33, where soothing scents waft through the air as expert therapists pamper you with blissful treatments designed to rejuvenate both body and mind.

Romantic Escape - Stroll hand-in-hand along the pristine beach, followed by a candlelit dinner at Cafe Amalfi, where the soft glow of sunset casts enchanting shadows, making every meal a perfect memory.

Spa Breaks - With two sparkling pools waiting just outside your door, take a refreshing dip or unwind in a hot tub, enveloped in laughter and the sweet scent of ocean breeze, ensuring each moment feels like a private getaway.

Guest Experiences - Guests have delighted in the spacious rooms that offer both comfort and style, often remarking on the delightful surprise of live music at the bar, filling the evenings with warm melodies that linger long after the sun sets.

Nestled along the serene marina of Grande Dunes, the Marina Inn at Grande Dunes is an oasis of luxury just moments from the sparkling sands of Myrtle Beach. With an elegant blend of modern sophistication and rustic charm, this resort invites couples and luxury seekers to unwind in a tranquil setting where every detail whispers comfort and romance.

Romantic Getaway - Imagine evening strolls on a private balcony as the sun dips below the horizon, casting a golden hue over the waters. The intimate ambiance, accentuated by soft music wafting in from the nearby Anchor Café, sets the perfect scene for lovebirds looking to connect amidst natural beauty.

Spa & Relaxation - Surrender to the bliss of in-room spa services that transform your space into a sanctuary. Feel the tension melt away with skilled hands working their magic, or lose yourself in the bubbly embrace of a hot tub under a blanket of stars, creating unforgettable moments of serenity.

Outstanding Location - With easy access to both the vibrant heart of Myrtle Beach and the secluded calm of the marina, guests can explore eclectic local markets, indulge in designer shopping, or simply relish the sound of waves lapping against the dock—a harmonious blend of adventure and relaxation awaits.

Guest Experiences - After a day filled with beach adventures, the calming scent of freshly brewed coffee greeted guests each morning, perfectly complemented by an extraordinary breakfast spread that brought smiles even before the day's explorations. And just when they thought they'd seen it all, families marveled at the joyful laughter of children unearthing tiny shark teeth during delightful scavenger hunts right at the marina.

Nestled in the vibrant heart of Charleston, the Francis Marion Hotel is a luxurious sanctuary that seamlessly blends historic charm with modern elegance. Across from the lush expanse of Marion Square, this upscale retreat invites guests to immerse themselves in the enchanting rhythms of Southern culture, where each room whispers tales of yesteryear while offering every contemporary comfort.

Historic Charm - Step into a world where timeless elegance reigns; the hotel's decor reflects its storied past, adorned with vintage artworks and details that echo Charleston's rich history.

Culinary Delights - Savor the essence of Southern cuisine at the Swamp Fox Restaurant, where the air is filled with the intoxicating aroma of regional specialties, alongside live jazz that wraps around you like a warm embrace as you sip on expertly crafted cocktails.

Spa Retreat - Indulge in a day of pampering at the full-service spa, where soothing scents and tranquil sounds envelop you, creating an oasis of relaxation amidst the bustling city life right outside your door.

Guest Experiences - A guest recalls the delightful surprise of checking in early and enjoying a light meal in the cozy Swamp Fox, where the friendly staff made them feel instantly welcomed. The striking beauty of the hotel—a classic silhouette against the Charleston skyline—was only rivaled by the enticing smell of freshly brewed coffee wafting through the lobby.

Nestled along the pristine shores of Hilton Head Island, Marriott's Grande Ocean is a luxurious sanctuary where every detail whispers elegance and tranquility. The gentle sound of waves mingles with the scent of salt in the air, inviting you to unwind and embrace a world of indulgence and adventure amid lush landscapes and ocean vistas.

Beach Life - Step from your chic accommodations directly onto the sandy shores, where the golden sun kisses your skin and the rhythm of the tide beckons for lazy afternoons filled with laughter and exploration.

Spa Breaks - Indulge in rejuvenating treatments that awaken your senses; the soothing aromas of essential oils and soft melodies create a serene escape, allowing you to melt away the stresses of everyday life as you bask in total relaxation.

Active Holiday - With opportunities for biking, kayaking, and minigolf, every day offers new adventures—vibrant paths weave through the surrounding nature, while the sounds of friendly competition echo as guests engage in spirited rounds of pool or table tennis.

Guest Experiences - One guest fondly recounted savoring their morning coffee on the balcony, surrounded by the sweet fragrance of blooming gardenias, the warm breeze carrying the distant laughter of children frolicking by the pool, marking it as one of their favorite moments of peace.

Nestled along the pristine shores of Hilton Head Island, the Sonesta Resort invites you to indulge in a blend of coastal elegance and modern luxury. With waves gently lapping at the beach just steps away, this enchanting retreat offers a sanctuary where romance thrives and relaxation reigns supreme.

Beach Life - Step onto the warm sands and feel the ocean breeze caress your skin; at Sonesta, the beach is not just an amenity—it's an extension of your suite. Here, the sound of laughter from families mingles with the rhythmic crash of the waves, creating a vibrant backdrop for sun-soaked adventures.

Spa Breaks - Immerse yourself in tranquility at our full-service spa, where soothing aromas waft through the air as skilled hands knead away your stresses. Each treatment is a harmonious blend of revitalizing scents and expert techniques, leaving you renewed and ready to embrace the island's serene beauty.

Romantic Getaway - Private balconies and patios beckon, offering breathtaking views of the Atlantic Ocean as the sun sets in a blaze of color. Enjoy intimate dinners at Seacrest Restaurant, where expertly crafted dishes pair beautifully with the ambient sounds of distant waves, setting the stage for unforgettable moments.

Guest Experiences - As you sip a refreshing cocktail by the pool, the air is filled with the enticing aroma of grilled dishes from The Pavilion, mingling with the salty sea breeze. Families bustle nearby, their children giggling during movie nights under the stars, while couples steal quiet moments on their luxurious balconies, soaking in the stunning sunset hues.

Nestled directly along the sun-kissed shores of Myrtle Beach, Anderson Ocean Club and Spa by Oceana Resorts invites you to discover a sanctuary of luxury and relaxation. With its captivating ocean views and serene ambiance, this upscale retreat is ideal for couples seeking romance, families in search of adventure, and wellness enthusiasts eager for rejuvenation.

Total Relaxation - Indulge in pure bliss at Awakening Spa, where the gentle sounds of waves and soothing fragrances envelop you as skilled therapists work their magic with signature treatments that leave you feeling utterly renewed.

Beach Life - Step outside to feel the warm sand between your toes and the refreshing ocean breeze against your skin, as you bask in the beauty of beachfront access just moments from your luxurious accommodations.

Romantic Break - Share intimate sunsets on your private balcony, sipping expertly crafted cocktails from B Bar as the horizon blushes with color, creating the perfect backdrop for cherished memories.

Guest Experiences - Guests often find themselves enchanted by the inviting atmosphere; the vibrant laughter around the pools mingles with the scent of saltwater, while the friendly bartenders add a touch of charm, making each visit feel like a homecoming.