The 4 Best Luxury Hotels with Spa in Indianapolis (2025)

Nestled in the heart of the Midwest, Indianapolis is a city that artfully marries its rich history with contemporary vibrancy. Stroll through the picturesque gardens of White River State Park or admire the stunning architecture of the Soldiers and Sailors Monument in the bustling downtown area. Known for its dynamic cultural scene, from the renowned Indianapolis Museum of Art to the spirited ambiance of Mass Ave, this capital city entices travelers with its unique charm and culinary delights. When it comes to luxury accommodations, Indianapolis shines brightly, offering an array of exceptional hotels that cater to discerning guests. The Conrad Indianapolis stands out with its sophisticated elegance and prime location near cultural landmarks, while the Ironworks Hotel Indy enchants with its industrial-chic design and local art flair. For those seeking an extraordinary experience, the 21c Museum Hotel boasts a blend of modern art and upscale comfort, making it a true gem. Explore our collection of Indianapolis luxury hotels with spa amenities, and begin planning your unforgettable getaway today.

Top Luxury Hotels in Indianapolis

luxury hotels in Indianapolis

Conrad Indianapolis

Hotel
50 West Washington Street, Indianapolis, IN 46204, USA

Nestled in the vibrant heart of downtown Indianapolis, Conrad Indianapolis offers a sanctuary of refined elegance and modern design. With its chic atmosphere, breathtaking art adorning every corner, and the soft glow of ambient lighting, this upscale retreat invites couples and luxury seekers alike to indulge in an exquisite escape.

Total Relaxation - Unwind at the on-site Conrad Spa, where curated treatments envelop you in tranquility, leaving you rejuvenated and glowing. Each treatment is executed with finesse, ensuring that your visit feels like a personalized journey toward complete wellness.

Outstanding Location - Perfectly positioned along the Indianapolis Cultural Trail, you’re just steps away from iconic sights like Monument Circle and the dynamic Indiana Convention Center. The city’s vibrant energy surrounds you, offering the perfect backdrop for leisurely strolls or spirited cultural explorations.

Chic Hotel Entertainment - The Lounge provides a sophisticated yet inviting atmosphere, where the clink of wine glasses complements the gentle hum of conversation. Guests relish in the curated selection of drinks while soaking up the exquisite decor, which transforms the lobby into a gallery of modern artistry.

Guest Experiences - Picture yourself wrapped in plush bathrobes, slipping into the marbled bathroom where a luxurious TV mirror reflects your contentment. Guests often reminisce about the delightful smell of fresh coffee wafting through the halls each morning, paired with the sound of welcoming greetings from the friendly staff, making every moment feel special.

luxury hotels in Indianapolis

Ironworks Hotel Indy

Hotel
2721 East 86th Street, Indianapolis, IN 46240, USA

Nestled in the vibrant heart of Indianapolis’ north side, Ironworks Hotel Indy is more than a boutique stay; it’s a romantic retreat where modern elegance meets rustic charm. With its tantalizing aromas wafting from upscale dining and an inviting rooftop lounge that beckons couples to unwind beneath starry skies, this hotel promises a luxurious yet intimate escape for discerning travelers.

Chic Accommodations - Every room at Ironworks balances sophisticated rustic décor with contemporary comforts, featuring plush bedding and walk-in showers framed by frosted glass—an indulgent treat for couples seeking seclusion and style.

Culinary Discoveries - Savor craft cocktails and exquisite dishes at Provisions, where the bartenders greet you with genuine warmth as you sip drinks infused with local flavors, setting the stage for memorable evenings filled with laughter and connection.

Wellness & Relaxation - The sleek fitness center invites guests to maintain their routines, while the serene atmosphere throughout the hotel encourages moments of quiet reflection—perfect for wellness enthusiasts looking to recharge amidst urban excitement.

Guest Experiences - Guests often speak fondly of the delightful scent that greets them upon entering, reminiscent of rich coffee and artisanal pastries, creating a warm ambiance that feels like home. The enchanting raindrop shower has become a highlight, providing a soothing experience that guests can't stop raving about, making each moment spent there feel refreshingly special.

luxury hotels in Indianapolis

21c Museum Hotel Louisville

Hotel
700 West Main Street, Louisville, KY 40202, USA

Nestled in the heart of downtown Louisville, the 21c Museum Hotel seamlessly blends contemporary art with luxurious accommodations, crafting an enchanting retreat for couples and cultural explorers alike. As you step into this vibrant space, the air is infused with a sense of creativity, inviting you to indulge in both relaxation and artistic inspiration.

Artworks & Culture - Immerse yourself in a dynamic fusion of art and hospitality, where each corner reveals thought-provoking installations that spark conversation and ignite your imagination.

Outstanding Location - Ideally situated just steps away from the city's iconic attractions, venture out to discover the rich history of Louisville or savor the local culinary scene without ever needing to stray far from your elegant oasis.

Spa & Wellness - Unwind in the tranquil spa, where soothing scents of essential oils mingle with soft music, providing an escape from the hustle and bustle of city life while rejuvenating your body and spirit.

Guest Experiences - Guests often recount the moment they first entered their spacious room, greeted by plush bedding and the subtle scent of fresh lavender; it's a cozy haven that makes you feel instantly at home, complemented by the friendly staff who remember your name as if you were family.

luxury hotels in Indianapolis

Omni Louisville Hotel

Hotel
400 South 2nd Street, Louisville, KY 40202, USA

Nestled in the vibrant heart of downtown Louisville, the Omni Louisville Hotel is an oasis of elegance and sophistication. As you step inside, the warm glow of curated art pieces beckons, while the gentle hum of laughter from the lively speakeasy envelops you, promising unforgettable moments amidst luxury and charm.

City Style - Experience the pulse of Louisville as you stroll through its picturesque streets, with local markets, historic landmarks, and the iconic KFC Yum! Center just steps away from your door.

Total Relaxation - Unwind in spacious rooms adorned with plush furnishings that cradles you in comfort; the scent of fresh linens mingles with the subtle notes of gourmet meals wafting from nearby restaurants.

Spa Breaks - Indulge in rejuvenating spa treatments that blend modern wellness with Southern hospitality, inviting you to melt away your cares in tranquility after a day of exploration.

Guest Experiences - As guests sink into the firm embrace of their luxurious beds, many have remarked on the serene ambiance punctuated only by soft whispers and the distant echo of clinking glasses from the bustling bar—creating a delightful contrast to the peaceful retreat found within.

Other great option in Indianapolis

luxury hotels in Indianapolis
5830 North Post Road, Indianapolis, IN 46216, US
8.8
641 reviews
From $125

Guest Review: The showers were amazing! Beautiful scenery, and very peacefully quiet!

Indianapolis Luxury Hotels on the Map

Frequently Asked Questions

For an indulgent experience, consider staying at Conrad Indianapolis, known for its top-notch spa services and luxurious accommodations. Another great option is the Omni Louisville Hotel, where you can enjoy rejuvenating treatments in a serene environment while being close to local attractions.

Yes! The Ironworks Hotel Indy offers spacious rooms and family-friendly amenities alongside its luxurious spa services. Alternatively, the Omni Louisville Hotel provides a welcoming atmosphere for families, complete with a kids' program and relaxing spa options for adults.

For a romantic getaway, consider the Conrad Indianapolis, which features elegant accommodations and a tranquil spa perfect for couples. The 21c Museum Hotel Louisville also offers a unique, artistic ambiance along with pampering spa experiences designed for two.

The Ironworks Hotel Indy combines contemporary design with affordability, offering luxurious spa treatments without breaking the bank. Additionally, the Omni Louisville Hotel features competitive rates while providing fantastic spa services and upscale amenities.

Explore the breathtaking cityscapes from the Conrad Indianapolis, which boasts stunning views along with its luxurious spa offerings. The Omni Louisville Hotel also features panoramic vistas and a well-regarded spa, making it a top choice for relaxation and scenery.