The 13 Best Luxury Hotels with Spa in Northern Aegean Islands (2025)

Nestled between the azure waters of the Aegean Sea and the lush landscapes of verdant hills, the Northern Aegean Islands offer a captivating blend of natural beauty and rich history. From the charming streets of Chios, dotted with medieval mastic villages, to the serene beaches of Samos, where ancient ruins whisper tales of the past, every corner of this enchanting archipelago invites exploration. The luxury hotel scene here reflects this idyllic charm, showcasing exclusive properties that elevate the art of hospitality. At Casa Cook Samos—an adults-only sanctuary—you can indulge in minimalist design and curated experiences tailored for ultimate relaxation. Meanwhile, Doryssa Seaside Resort offers stunning views and a tranquil ambiance perfect for family getaways or romantic escapes. For those seeking rejuvenation, PEARL ISLAND CHIOS HOTEL & SPA provides a lavish retreat with world-class wellness facilities and gourmet dining options. Embrace the allure of the Northern Aegean Islands Luxury Hotels with Spa as you plan your unforgettable getaway, where every moment promises to be nothing short of extraordinary.

Top Luxury Hotels in Northern Aegean Islands

luxury hotels in Northern Aegean Islands

Casa Cook Samos - Adults only

Hotel
Potokaki Pythagorion, Pythagoreio, 83103, Greece

Nestled along the sun-kissed shores of Pythagoreio, Casa Cook Samos invites you to indulge in an oasis of tranquility and elegance, exclusively for adults. With its chic design harmonizing with lush gardens and sweeping sea views, this luxurious retreat offers a romantic getaway where every moment feels like a cherished memory.

Spa and Relaxation - Immerse yourself in bliss at our Turkish bath, where aromatic essences waft through steam-filled air, creating a serene escape perfect for rejuvenation. Here, tranquility envelops you as you surrender to soothing treatments that leave your mind and body recharged.

Outstanding Location - A mere stroll from Potokaki Beach, the hotel’s prime location offers easy access to soft sands and crystal waters, making impromptu beach days effortless. Picture yourself wandering the shoreline, the gentle lapping of waves serenading your every step.

Chic and Intimate Design - Each room is a sanctuary of style, featuring modern furnishings and subtle textures that entice the senses. Guests have relished the calming ambiance complemented by thoughtful details—a cozy coffee station here, a private balcony overlooking the sea there—perfect for unwinding after a day of exploration.

Guest Experiences - Guests rave about the unforgettable breakfast, where the aroma of freshly baked pastries mingles with the scent of rich coffee, creating a morning ritual that sets the tone for the day. One visitor fondly recalled the quietude of their room, enhanced by the soft rustle of leaves outside, inviting a peaceful nap amidst the vibrant gardens.

luxury hotels in Northern Aegean Islands

Doryssa Seaside Resort

Resort
Main Street, Pythagoreio, 83103, Greece

Nestled along the sun-kissed shores of Samos, Doryssa Seaside Resort is a sanctuary where luxury and nature intertwine. With the gentle sound of waves lapping against golden sands and the Aegean Sea's azure waters stretching to the horizon, this exquisite resort invites you to unwind in an oasis of elegance and tranquility, just moments from the charming village of Pythagoreio.

Total Relaxation - Immerse yourself in serene indulgence at the resort’s lush spa, where the fragrant scents of essential oils mingle with the soft rustle of leaves, creating a haven for rejuvenation. Choose from a curated menu of treatments designed to harmonize body and mind, all while surrounded by vibrant gardens that breathe life into your experience.

Beach Life - With direct access to a long sandy beach sheltered from the wind, relish in the golden sun as you sink your toes into soft sand. The crystal-clear waters beckon for a refreshing dip, offering a perfect backdrop for lazy afternoons spent lounging under the shade of palm trees while sipping on a chilled drink.

Romantic Break - Doryssa is an enchanting escape for couples, boasting intimate nooks and breathtaking sunset views that set the stage for romantic evenings. Enjoy a candlelit dinner at the Asterias restaurant, where every flavor bursts forth like a love letter from the sea, leaving you both enchanted by the culinary artistry of the region.

Guest Experiences - As you stroll through the picturesque village nearby, the sweet aroma of freshly baked pastries drifts through the air, inviting you to indulge in local delights. Friendly faces greet you, especially Anna and Sophia, who make you feel like cherished guests rather than mere visitors—a warmth that transforms your stay into a memorable gathering of hearts.

luxury hotels in Northern Aegean Islands

PEARL ISLAND CHIOS HOTEL & SPA

Hotel
8 Leoforos Enoseos, Chios, 82100, Greece

Nestled in the enchanting embrace of Chios, the Royal Pearl Island Hotel and Spa is a sanctuary where luxury meets tranquility. Just a stone's throw from the shimmering waters of Chios Town Beach, this hotel offers an elegant escape adorned with modern comforts and attentive service, creating an atmosphere that whispers romance and relaxation in every corner.

Spa Retreats - Indulge in a world of serenity at the hotel's spa, where the gentle sound of flowing water and soothing aromas create a haven for wellness enthusiasts. Each treatment room invites you to unwind as expert hands melt away your cares, leaving only pure bliss in their wake.

Chic Poolside Oasis - With two distinct pools catering to every whim—one heated for cozy moments and another refreshing for sun-soaked adventures—guests can bask in luxurious leisure. The soft lapping of water and the warmth of the sun create an idyllic setting for intimate conversations or solitary reflections under the azure skies.

Culinary Delights - Savor a buffet breakfast that tantalizes the senses, crafted with local ingredients bursting with flavor. The presentation is an art form, as vibrant colors and fragrant herbs awaken your appetite, while friendly staff ensure that each delicious bite fuels your adventures in this charming locale.

Guest Experiences - As guests wandered the serene pathways of the hotel, they often remarked on the soothing aroma of fresh coffee wafting through the air during breakfast. The warmth of the sun kissed their skin as they lounged by the pool, enjoying the attentive service of staff who felt more like family, always ready with a smile or a kind word.

luxury hotels in Northern Aegean Islands

Varos Village Boutique Hotel

Hotel
Main Street, Varos, 81401, Greece

Nestled in the charming village of Varos, Greece, Varos Village Boutique Hotel offers an exquisite blend of modern elegance and tranquil seclusion. With every corner adorned with thoughtful design and a serene atmosphere that whispers luxury, this boutique oasis invites couples, wellness seekers, and cultural explorers to unwind and indulge in a truly romantic escape.

Chic Accommodations - Each room radiates sophistication with carefully curated decor, plush furnishings, and a unique touch that feels like a personal retreat. Enjoy the gentle breeze on your private balcony while sipping freshly brewed coffee, or luxuriate in the soothing ambiance enhanced by high-quality amenities.

Gastronomic Delights - Savor the flavors of Greece at the hotel's restaurant, where homemade pastries and fresh local ingredients create a delightful breakfast experience in a stunning setting. The warm aroma of baked goods mingles with the morning sea air as you plan your adventures over delicious fare.

Serene Retreat - The seasonal outdoor swimming pool beckons for leisurely afternoons, surrounded by lush gardens that invite tranquility. Take a pause under the sun's golden rays, perhaps indulging in a rejuvenating soak in the hot tub while listening to the soft rustle of leaves overhead.

Guest Experiences - Upon arrival, guests are greeted not just by staff but by heartfelt hospitality; Ioanna’s radiant smile makes you feel right at home, as if you've stepped into a cherished friend's abode. As you settle into your beautifully quiet room, the only sounds are the distant waves and the comforting hum of a well-appointed space, inviting restful nights.

luxury hotels in Northern Aegean Islands

Proteas Blu Resort

Hotel
Main Street, Pythagoreio, 83103, Greece

Nestled along the shimmering shores of Pythagoreio, Proteas Blu Resort beckons with an air of serene luxury and intimate romance. With its pristine cove and two secluded beaches, this exquisite retreat envelops guests in a world where every moment is adorned with the soft sounds of lapping waves and the scent of Mediterranean blooms wafting through sea breezes.

Total Relaxation - With plush sun beds lining the beaches and attentive beach service at your fingertips, indulge in lazy afternoons under the sun or rejuvenate in the peaceful indoor pool, where the gentle echo of water creates a tranquil ambiance to unwind.

Spa Breaks - Elevate your stay with personalized wellness treatments that promise a harmonious blend of relaxation and rejuvenation—breathe in the soothing aromas of essential oils as skilled therapists work their magic, leaving you refreshed and revitalized.

Outstanding Location - Perched gracefully on a stunning coastline, each elegant room offers breathtaking sea views, inviting you to awaken to the golden hues of dawn while the tranquil sound of the ocean sets the perfect tone for your day.

Guest Experiences - As dusk settles, the soft glow of the moon illuminates the terrace where guests share stories over gourmet dishes; the laughter and clinking of glasses mingle with the distant melody of waves, creating an atmosphere rich with warmth and connection. One guest recalled savoring the delightful taste of freshly prepared local cuisine, saying it felt like a hidden treasure waiting to be uncovered.

luxury hotels in Northern Aegean Islands

Theofilos Paradise Boutique Hotel

Hotel
Skra 7, Mytilene, 81100, Greece

Nestled in the heart of Mytilini, Theofilos Paradise Boutique Hotel is a haven of tranquility and elegance, where the whispers of history blend seamlessly with modern luxury. Just a short stroll from the sun-kissed shores of Tsamakia Beach, this enchanting hotel invites you to indulge in its serene atmosphere, characterized by exquisite design and personal touches that make each moment feel special.

Romantic Retreat - With its intimate ambiance and luxurious rooms featuring hydromassage showers, Theofilos Paradise provides the perfect backdrop for couples seeking a romantic getaway. Picture yourself basking under the stars at the rooftop pool, cocktail in hand, as you savor the gentle sea breeze and the glow of the surrounding city lights.

Culinary Delights - Start your day with an authentic Greek breakfast served in a chic dining room, where fragrant coffee mingles with the aroma of fresh pastries. Guests have raved about the charming staff who go the extra mile, such as personally brewing traditional Greek coffee, ensuring each breakfast feels like a warm embrace.

Historic Charm - Housed in a lovingly restored mansion dating back to 1912, Theofilos Paradise tells a story of timeless elegance and heritage. The reception hall, adorned with classic marble and vintage details, enchants visitors, making them feel as if they’ve stepped into a beautifully curated gallery that speaks to the island's rich past.

Guest Experiences - As guests unwind in the inviting lounge, the crackling sound of the fireplace fills the air, complementing the comforting scent of freshly brewed coffee. One traveler fondly recalled the delight of closing their balcony doors to silence the lively sounds of the nearby bar, creating a peaceful retreat without sacrificing convenience.

luxury hotels in Northern Aegean Islands

Mythical Coast Wellness Retreat

Hotel
Agrilia Kratigou, Mytilene, 81100, Greece

Nestled along the serene shores of Mytilini, the Mythical Coast Wellness Retreat beckons with an enchanting blend of luxury and tranquility. Here, romance flourishes amidst lush gardens and stunning sea views, inviting guests to unwind and indulge in a setting that feels both upscale and exquisitely private.

Spa Breaks - Experience total relaxation with rejuvenating treatments in our state-of-the-art spa, where the soothing sounds of nature and the gentle scents of essential oils create an atmosphere of pure bliss.

Romantic Getaways - Escape to a world of intimacy as you savor candlelit dinners on the terrace, overlooking the twinkling sea at sunset, while sharing laughter and whispers that drift away into the starry night.

Outstanding Location - Just moments from the airport yet blissfully secluded, the retreat offers easy access to cycling adventures and cultural explorations, allowing you to seamlessly blend adventure with relaxation.

Guest Experiences - As you step out onto your private balcony, the scent of blooming flowers mingles with the salt air, reminding you of the peaceful oasis surrounding you. You can't help but smile as soft chatter from nearby guests blends harmoniously with the sound of water lapping against the shore, creating a symphony of serenity.

luxury hotels in Northern Aegean Islands

Sea View Resorts & Spa

Resort
Karfas, Karfas, 82100, Greece

Nestled along the shimmering coast of Karfás, Sea View Resorts & Spa wraps you in a harmonious blend of luxury and tranquility. With every corner whispering romance—from the stunning Aegean vistas to the soothing sounds of waves lapping at the shore—this is where privacy meets indulgence, creating an oasis for couples, wellness seekers, and adventurous souls alike.

Panoramic Poolside Bliss - Bask in the sun beside the infinity pool, where breathtaking sea views stretch endlessly. The gentle breeze carries the scent of lavender from nearby gardens, ensuring each dip feels like a rejuvenating escape into paradise.

Culinary Delights with a View - Savor gourmet flavors crafted from local ingredients at the hotel restaurant, where meals are taken on a terrace that overlooks the azure waters. Imagine the taste of fresh seafood paired with the rich aroma of Mediterranean herbs, all while listening to the soft rustle of palm leaves overhead.

Wellness Retreat - Step into serenity at the spa, where the air is infused with calming essential oils, inviting you to unwind in its hot tub or sauna. Each treatment is designed to envelop you in relaxation, from aromatic massages to invigorating facials, making it the perfect sanctuary after a day of exploration.

Guest Experiences - Guests often find themselves enchanted by the remarkable hospitality of the staff, with one mentioning how 'mikri' Angeliki at reception took the time to share hidden gems around Chios, her voice warm and inviting. Even the breakfast buffet became a cherished moment, overflowing with local delicacies that filled the air with tantalizing aromas, promising a delightful start to the day.

luxury hotels in Northern Aegean Islands

Cavos Bay Hotel & Studios

Hotel
Main Street, Armenistis, 83301, Greece

Nestled on the tranquil hillsides of Armenistis, Cavos Bay Hotel & Studios offers an enchanting escape where the gentle whispers of the Aegean Sea accompany your every moment. Here, traditional architecture harmonizes with modern luxury, creating a serene retreat adorned with breathtaking views and intimate nooks for romantic interludes or quiet contemplation.

Outstanding Location - Perched on six tiers overlooking the sparkling Aegean, each room at Cavos Bay reveals a unique vista that captivates the senses—the rhythmic sound of waves crashing against rugged rocks below, which becomes a soothing soundtrack to your stay.

Romantic Break - With saltwater pools that shimmer under the golden sun and cozy verandas perfect for sunset toasts, this hotel is a haven for couples seeking intimacy amidst stunning natural beauty, where every touchpoint feels crafted just for you.

Total Relaxation - The air is infused with the scent of blooming wildflowers as you stroll through lush gardens or unwind in a private hot tub, cradled by spectacular views that invite you to linger longer and savor the serene ambiance.

Guest Experiences - One guest was enamored by the warmth of the evenings spent poolside, where the water felt like velvet against their skin as they chatted softly while the sun dipped below the horizon, painting the sky in hues of orange and pink—pure bliss that made them wish for time to stand still.

luxury hotels in Northern Aegean Islands

Reges, a Luxury Collection Resort & Spa, Cesme

Hotel
Boyalik Mahallesi 3198/1, 35930 Çeşme, Turkey

Nestled along the sun-kissed shores of Çeşme, Reges, a Luxury Collection Resort & Spa, beckons with an aura of sophistication and tranquility. As you step inside, the gentle sound of waves mingles with the scent of Mediterranean blooms, creating an oasis tailored for romance and relaxation, all just moments from the pristine Boyalik Beach.

Total Relaxation - Indulge in the resort's exquisite spa, where the soothing aroma of eucalyptus fills the air as you unwind in the luxurious hammam or soak in the rejuvenating hot tub, perfect for unwinding after a day spent exploring nearby treasures.

Beach Life - Experience the serenity of your private beach area, where golden sands meet crystal-clear waters, inviting you to bask in the sun with a refreshing drink, while the soft rustle of palm leaves overhead creates a soundtrack of blissful escape.

Culinary Delights - Savor exceptional culinary experiences at the on-site restaurant, where each dish, from Italian delicacies to vibrant Mediterranean flavors, is crafted with fresh local ingredients, tantalizing your taste buds against the backdrop of stunning sea views.

Guest Experiences - Awaking to a symphony of birdsong, guests delight in the lavish breakfast spread that features everything from fluffy pancakes to artisanal cheeses, served with warm smiles by attentive staff who seem to anticipate every need with charming efficiency.

luxury hotels in Northern Aegean Islands

Boyalik Beach Hotel & Spa Cesme

Hotel
3200 Sok. No:1 Boyalik Mevkii , 35930 Çeşme, Turkey

Nestled on the sun-drenched shores of Çeşme, Boyalik Beach Hotel & Spa invites you to indulge in a luxurious escape where the gentle sound of waves and soft sea breezes create an idyllic atmosphere for relaxation. Each moment spent here feels personal, from the serene private beach to the elegant spa experiences that beckon whispers of tranquility.

Beach Life - Step onto the hotel's private beach, where plush loungers await under generous parasols, and the crystal-clear waters invite you for a refreshing dip. Here, the smell of saltwater mingles with the aroma of tantalizing snacks served just steps away from your sun-kissed spot.

Spa Breaks - Immerse yourself in a haven of wellness at the spa, where the soothing scents of essential oils fill the air, and skilled therapists whisk you into blissful relaxation with rejuvenating treatments. The Turkish bath experience is not to be missed; as you sink into the warmth, the subtle sounds of water cascading around you melt your cares away.

Culinary Delights - Savor the diverse and delicious offerings at the buffet, where the chefs take pride in crafting local Turkish cuisine that dances on your palate. The delightful ambiance is only enhanced by the attentive staff, always ready to refill your plate or share a warm smile, making each meal feel like a festive gathering.

Guest Experiences - Imagine lounging on the pier as the sun dips below the horizon, when the friendly staff arrives with cushions and towels, effortlessly catering to your every desire. A couple mentioned their delight at discovering the impressive variety at dinner, finding themselves enchanted by flavors that felt both familiar and exotic, all while the ocean breeze rustled through the palm trees overhead.

luxury hotels in Northern Aegean Islands

Swissotel Resort And Spa Cesme

Hotel
Sifne Cad. No: 35, Ilica, 35930 Çeşme, Turkey

Nestled in the sun-kissed embrace of Ilica, where the azure Aegean kisses the golden sands, Swissôtel Resort and Spa Çeşme is a sanctuary of refined elegance. This upscale haven captures the essence of relaxation and romance, inviting guests to unwind amid lush olive orchards and soothing thermal springs, offering an experience that transcends mere luxury.

Spa Retreat - Immerse yourself in the serenity of Pürovel Spa & Sport, where mineral-rich thermal waters invigorate your senses while the aroma of Swiss essential oils envelops you—a truly rejuvenating escape amidst tranquil surroundings.

Culinary Delights - Embark on a gastronomic journey with our master chefs, whose artistry brings together Turkish, Far Eastern, and Italian flavors; each bite a celebration of local ingredients that tantalizes the palate and warms the soul.

Stunning Accommodations - Experience chic comfort in our spacious guest rooms and suites, each boasting breathtaking sea views and designed with thoughtful touches—like crisp linens and plush bedding—that make you feel right at home, even as waves serenade you to sleep.

Guest Experiences - Morning sunlight spills through large windows, illuminating the room while the scent of fresh pastries wafts from the breakfast buffet downstairs. Families share laughter at the beach, their children building castles in the fine sand, while friendly staff members greet everyone with warm smiles, turning moments into memories.

luxury hotels in Northern Aegean Islands

Imren Han Hotel - Special Category

Hotel
Yeni Mecidiye Mah.1039 Sok.No:26, 35950 Alaçatı, Turkey

Nestled in the enchanting village of Alaçatı, Imren Han Hotel - Special Category provides a serene oasis where luxury meets tradition. Surrounded by charming cobblestone streets and vibrant bougainvillea, this boutique retreat invites couples and wellness enthusiasts alike to indulge in an unforgettable getaway steeped in tranquility and understated elegance.

Romantic Getaway - Immerse yourself in intimate moments as you sip on locally-sourced wine while lounging under the stars by the shimmering seasonal pool, serenaded by the gentle rustle of leaves in the warm evening breeze.

Spa & Relaxation - Rejuvenate your senses in the hotel's tranquil hammam and sauna, where the soothing aroma of eucalyptus fills the air, creating a perfect ambiance for unwinding after a day of exploring or lounging by the pool.

Culinary Delights - Savor a delightful continental breakfast each morning, featuring freshly baked pastries and fragrant coffee, all served al fresco on a sun-dappled terrace surrounded by lush greenery, making every bite a feast for the senses.

Guest Experiences - One guest recounted how the delightful staff went out of their way, remembering their favorite tea blend and surprising them with it during a leisurely afternoon by the garden—a simple gesture that transformed a pleasant stay into a cherished memory.

Best Luxury Hotels that guests love in Northern Aegean Islands

luxury hotels in Northern Aegean Islands
Agrilia Kratigou, Mytilene, 81100, Greece
8.2
857 reviews
From $215

Guest Review: Perfect five star hotel . Very clean , great food , luxury and very friendly

luxury hotels in Northern Aegean Islands
Skra 7, Mytilene, 81100, Greece
9.0
520 reviews
From $155

Guest Review: Attitude of the staff towards us was so kind. They were so polite. They tried to do what we wished.

luxury hotels in Northern Aegean Islands
Karfas, Karfas, 82100, Greece
8.4
485 reviews
From $186

Guest Review: We would like to thank Eleanna Kappa and the other hotel staff for hosting us in the nicest way during our stay at the hotel. We would also like to point out the richness of the breakfast.

Other great option in Northern Aegean Islands

luxury hotels in Northern Aegean Islands
Pythagoreio, Pythagoreio, 83103, GR
8.3
127 reviews
From $98

Guest Review: The property is taken care of very well and the breakfast was amazing for its price. The host was very helpful :-)

Northern Aegean Islands Luxury Hotels on the Map

Frequently Asked Questions

For an indulgent experience, consider the Reges, a Luxury Collection Resort & Spa, Cesme Reges, a Luxury Collection Resort & Spa, Cesme which boasts extensive spa services. PEARL ISLAND CHIOS HOTEL & SPA PEARL ISLAND CHIOS HOTEL & SPA also offers luxurious treatments amidst stunning surroundings.

Yes! For a romantic getaway, the Proteas Blu Resort Proteas Blu Resort provides breathtaking views and intimate settings. Additionally, Casa Cook Samos - Adults only Casa Cook Samos - Adults only is perfect for couples seeking a peaceful retreat with modern design.

Food lovers will delight in the culinary offerings at Doryssa Seaside Resort Doryssa Seaside Resort, known for its fresh local ingredients. Theofilos Paradise Boutique Hotel Theofilos Paradise Boutique Hotel also features delicious dining options, emphasizing traditional Greek flavors.

For spectacular views, Cavos Bay Hotel & Studios Cavos Bay Hotel & Studios is highly recommended, offering picturesque vistas of the Aegean Sea. Similarly, Varos Village Boutique Hotel Varos Village Boutique Hotel showcases charming landscapes, perfect for travelers wanting scenic beauty.

Families will love Swissotel Resort and Spa Cesme Swissotel Resort And Spa Cesme, which has activities for all ages. Boyalik Beach Hotel & Spa Cesme Boyalik Beach Hotel & Spa Cesme also caters to families, featuring spacious accommodations and kid-friendly amenities.

For a boutique experience on a budget, Imren Han Hotel - Special Category Imren Han Hotel - Special Category offers charm without breaking the bank. Varos Village Boutique Hotel Varos Village Boutique Hotel is another excellent choice, combining affordability with unique design.