The 7 Best Luxury Hotels with Spa in Missouri (2026)

When it comes to luxury hotels with spas in Missouri, consider The Ritz-Carlton, St. Louis The Ritz-Carlton, St. Louis for its elegant spa and fine dining options. The Four Seasons St. Louis Four Seasons St. Louis is another fantastic choice, featuring a world-class spa and stunning views of the Gateway Arch.

For a romantic getaway, indulge in the elegant charm of The Raphael Hotel, Autograph Collection The Raphael Hotel, Autograph Collection, known for its intimate atmosphere and luxurious amenities. You might also enjoy Chateau on the Lake Resort Spa and Convention Center Chateau on the Lake Resort Spa and Convention Center, which offers breathtaking lake views and a full-service spa perfect for couples.

Food lovers will relish their stay at The Ritz-Carlton, St. Louis The Ritz-Carlton, St. Louis, where gourmet dining experiences await. Equally impressive is The Lodge at Old Kinderhook The Lodge at Old Kinderhook, boasting a farm-to-table restaurant that highlights local flavors and ingredients.

Families can unwind at Camden on the Lake Resort Camden on the Lake Resort, which offers spacious accommodations and kid-friendly activities. Another excellent option is The Lodge at Old Kinderhook The Lodge at Old Kinderhook, featuring facilities that cater to both relaxation and family fun, along with a lovely spa.

For magnificent views, check out Chateau on the Lake Resort Spa and Convention Center Chateau on the Lake Resort Spa and Convention Center, set against the backdrop of Table Rock Lake. Also, Lookout Point Lakeside Inn Lookout Point Lakeside Inn provides picturesque lake vistas and an intimate ambiance, making it a delightful retreat.