The 7 Best Luxury Hotels with Spa in Lesbos (2025)

Nestled in the Aegean Sea, Lesbos is a captivating island brimming with rich history, breathtaking landscapes, and vibrant culture. From the charming streets of Mytilene to the serene beaches along the mythical coast, visitors are drawn to the island's stunning architecture, including ancient castles and picturesque fishing villages. The culinary scene thrives on fresh seafood and local delicacies, making every meal a celebration of flavors and traditions. For those seeking an indulgent escape, the luxury hotel scene on Lesbos is equally enchanting. Theofilos Paradise Boutique Hotel offers a blend of classic elegance and modern comfort, perfect for immersing oneself in the island’s beauty. Meanwhile, Mythical Coast Wellness Retreat presents a sanctuary for relaxation with its holistic spa treatments and serene coastal views, ideal for rejuvenation. Just across the bay, D - Resort Ayvalık captivates guests with its chic design and exceptional service. Discover the allure of Lesbos and explore our collection of Lesbos, Greece luxury hotels with spa offerings, inviting you to embark on an unforgettable journey.

Top Luxury Hotels in Lesbos

luxury hotels in Lesbos

Theofilos Paradise Boutique Hotel

Hotel
Skra 7, Mytilene, 81100, Greece

Nestled in the heart of Mytilini, Theofilos Paradise Boutique Hotel is a haven of tranquility and elegance, where the whispers of history blend seamlessly with modern luxury. Just a short stroll from the sun-kissed shores of Tsamakia Beach, this enchanting hotel invites you to indulge in its serene atmosphere, characterized by exquisite design and personal touches that make each moment feel special.

Romantic Retreat - With its intimate ambiance and luxurious rooms featuring hydromassage showers, Theofilos Paradise provides the perfect backdrop for couples seeking a romantic getaway. Picture yourself basking under the stars at the rooftop pool, cocktail in hand, as you savor the gentle sea breeze and the glow of the surrounding city lights.

Culinary Delights - Start your day with an authentic Greek breakfast served in a chic dining room, where fragrant coffee mingles with the aroma of fresh pastries. Guests have raved about the charming staff who go the extra mile, such as personally brewing traditional Greek coffee, ensuring each breakfast feels like a warm embrace.

Historic Charm - Housed in a lovingly restored mansion dating back to 1912, Theofilos Paradise tells a story of timeless elegance and heritage. The reception hall, adorned with classic marble and vintage details, enchants visitors, making them feel as if they’ve stepped into a beautifully curated gallery that speaks to the island's rich past.

Guest Experiences - As guests unwind in the inviting lounge, the crackling sound of the fireplace fills the air, complementing the comforting scent of freshly brewed coffee. One traveler fondly recalled the delight of closing their balcony doors to silence the lively sounds of the nearby bar, creating a peaceful retreat without sacrificing convenience.

luxury hotels in Lesbos

Mythical Coast Wellness Retreat

Hotel
Agrilia Kratigou, Mytilene, 81100, Greece

Nestled along the serene shores of Mytilini, the Mythical Coast Wellness Retreat beckons with an enchanting blend of luxury and tranquility. Here, romance flourishes amidst lush gardens and stunning sea views, inviting guests to unwind and indulge in a setting that feels both upscale and exquisitely private.

Spa Breaks - Experience total relaxation with rejuvenating treatments in our state-of-the-art spa, where the soothing sounds of nature and the gentle scents of essential oils create an atmosphere of pure bliss.

Romantic Getaways - Escape to a world of intimacy as you savor candlelit dinners on the terrace, overlooking the twinkling sea at sunset, while sharing laughter and whispers that drift away into the starry night.

Outstanding Location - Just moments from the airport yet blissfully secluded, the retreat offers easy access to cycling adventures and cultural explorations, allowing you to seamlessly blend adventure with relaxation.

Guest Experiences - As you step out onto your private balcony, the scent of blooming flowers mingles with the salt air, reminding you of the peaceful oasis surrounding you. You can't help but smile as soft chatter from nearby guests blends harmoniously with the sound of water lapping against the shore, creating a symphony of serenity.

luxury hotels in Lesbos

D - Resort Ayvalık

Hotel
Paşa Koyu, Seytan Sofrası Yolu Uzeri No:1 | Ayvalık | Balıkesir | Turkey , 10425 Ayvalık, Turkey

Nestled along the serene shores of Ayvalık, D - Resort Ayvalık invites you to indulge in a luxurious retreat where elegance meets nature's beauty. With its private beach area and breathtaking views of the azure sea, this sanctuary is perfect for couples seeking romance or wellness enthusiasts yearning for rejuvenation amidst lush gardens and modern amenities.

Romantic Escape - Elegant rooms with plush furnishings beckon you to unwind on your private balcony, where the gentle sound of waves lulls you into tranquility, making it the ideal setting for romantic evenings under the stars.

Culinary Delights - Start your day with an extravagant buffet breakfast that rivals brunches at top-tier restaurants. Each morning, immerse yourself in the aroma of freshly baked pastries and local delicacies, setting the stage for delightful culinary experiences throughout your stay.

Wellness Retreat - Rejuvenate your spirit in the state-of-the-art spa, where soothing scents of essential oils fill the air. Experience traditional hammam rituals or indulge in a relaxing massage while listening to the calming sounds of tranquil water features around you.

Guest Experiences - As you stroll through the resort, the enchanting scent of pinewood envelops you, and guests can’t help but marvel at how every corner exudes charm. One evening, a guest was touched when the attentive staff arranged for a surprise Turkish tea delivery right to their sunbed, a thoughtful gesture that perfectly encapsulated the exceptional service that defines D - Resort Ayvalık.

luxury hotels in Lesbos

Radisson Hotel Izmir Aliaga

Hotel
Necmettin Giritlioğlu Caddesi, Siteler Mahallesi, İzmir, Turkey

Nestled in the vibrant heart of İzmir, Radisson Hotel Izmir Aliaga invites you into a world of refined elegance and modern comforts. Picture yourself unwinding in beautifully appointed rooms that marry luxury with convenience, all while enveloped by the serene ambiance of lush gardens and tranquil terraces. Whether you're savoring exquisite Turkish cuisine or basking in the healing warmth of the sauna, this sanctuary promises an unforgettable escape.

Spa Breaks - Indulge in rejuvenation at our wellness center, where soothing aromas fill the air and expert hands work wonders on tired muscles. Experience total relaxation as steam wafts from the sauna, wrapping you in tranquility after a day of exploration.

Romantic Getaway - Craft the perfect love story in a setting designed for intimacy, where candlelit dinners blend seamlessly with breathtaking city views. Each evening whispers romance, inviting couples to create cherished memories under the star-studded sky.

Local Exploring - Step outside your luxurious haven and immerse yourself in the local culture, with historic sites and bustling markets just a stone's throw away. The sounds of lively street vendors and the scent of spices beckon you to discover the vibrant tapestry of İzmir life.

Guest Experiences - Guests have shared delightful moments like the exhilaration of enjoying morning coffee on their private balcony, sipping slowly while taking in the stunning garden views. One visitor remarked on the flawless cleanliness of their room, where every detail felt fresh and inviting, creating a cozy retreat after a busy day.

luxury hotels in Lesbos

PEARL ISLAND CHIOS HOTEL & SPA

Hotel
8 Leoforos Enoseos, Chios, 82100, Greece

Nestled in the enchanting embrace of Chios, the Royal Pearl Island Hotel and Spa is a sanctuary where luxury meets tranquility. Just a stone's throw from the shimmering waters of Chios Town Beach, this hotel offers an elegant escape adorned with modern comforts and attentive service, creating an atmosphere that whispers romance and relaxation in every corner.

Spa Retreats - Indulge in a world of serenity at the hotel's spa, where the gentle sound of flowing water and soothing aromas create a haven for wellness enthusiasts. Each treatment room invites you to unwind as expert hands melt away your cares, leaving only pure bliss in their wake.

Chic Poolside Oasis - With two distinct pools catering to every whim—one heated for cozy moments and another refreshing for sun-soaked adventures—guests can bask in luxurious leisure. The soft lapping of water and the warmth of the sun create an idyllic setting for intimate conversations or solitary reflections under the azure skies.

Culinary Delights - Savor a buffet breakfast that tantalizes the senses, crafted with local ingredients bursting with flavor. The presentation is an art form, as vibrant colors and fragrant herbs awaken your appetite, while friendly staff ensure that each delicious bite fuels your adventures in this charming locale.

Guest Experiences - As guests wandered the serene pathways of the hotel, they often remarked on the soothing aroma of fresh coffee wafting through the air during breakfast. The warmth of the sun kissed their skin as they lounged by the pool, enjoying the attentive service of staff who felt more like family, always ready with a smile or a kind word.

luxury hotels in Lesbos

Reges, a Luxury Collection Resort & Spa, Cesme

Hotel
Boyalik Mahallesi 3198/1, 35930 Çeşme, Turkey

Nestled along the sun-kissed shores of Çeşme, Reges, a Luxury Collection Resort & Spa, beckons with an aura of sophistication and tranquility. As you step inside, the gentle sound of waves mingles with the scent of Mediterranean blooms, creating an oasis tailored for romance and relaxation, all just moments from the pristine Boyalik Beach.

Total Relaxation - Indulge in the resort's exquisite spa, where the soothing aroma of eucalyptus fills the air as you unwind in the luxurious hammam or soak in the rejuvenating hot tub, perfect for unwinding after a day spent exploring nearby treasures.

Beach Life - Experience the serenity of your private beach area, where golden sands meet crystal-clear waters, inviting you to bask in the sun with a refreshing drink, while the soft rustle of palm leaves overhead creates a soundtrack of blissful escape.

Culinary Delights - Savor exceptional culinary experiences at the on-site restaurant, where each dish, from Italian delicacies to vibrant Mediterranean flavors, is crafted with fresh local ingredients, tantalizing your taste buds against the backdrop of stunning sea views.

Guest Experiences - Awaking to a symphony of birdsong, guests delight in the lavish breakfast spread that features everything from fluffy pancakes to artisanal cheeses, served with warm smiles by attentive staff who seem to anticipate every need with charming efficiency.

luxury hotels in Lesbos

Boyalik Beach Hotel & Spa Cesme

Hotel
3200 Sok. No:1 Boyalik Mevkii , 35930 Çeşme, Turkey

Nestled on the sun-drenched shores of Çeşme, Boyalik Beach Hotel & Spa invites you to indulge in a luxurious escape where the gentle sound of waves and soft sea breezes create an idyllic atmosphere for relaxation. Each moment spent here feels personal, from the serene private beach to the elegant spa experiences that beckon whispers of tranquility.

Beach Life - Step onto the hotel's private beach, where plush loungers await under generous parasols, and the crystal-clear waters invite you for a refreshing dip. Here, the smell of saltwater mingles with the aroma of tantalizing snacks served just steps away from your sun-kissed spot.

Spa Breaks - Immerse yourself in a haven of wellness at the spa, where the soothing scents of essential oils fill the air, and skilled therapists whisk you into blissful relaxation with rejuvenating treatments. The Turkish bath experience is not to be missed; as you sink into the warmth, the subtle sounds of water cascading around you melt your cares away.

Culinary Delights - Savor the diverse and delicious offerings at the buffet, where the chefs take pride in crafting local Turkish cuisine that dances on your palate. The delightful ambiance is only enhanced by the attentive staff, always ready to refill your plate or share a warm smile, making each meal feel like a festive gathering.

Guest Experiences - Imagine lounging on the pier as the sun dips below the horizon, when the friendly staff arrives with cushions and towels, effortlessly catering to your every desire. A couple mentioned their delight at discovering the impressive variety at dinner, finding themselves enchanted by flavors that felt both familiar and exotic, all while the ocean breeze rustled through the palm trees overhead.

Best Luxury Hotels that guests love in Lesbos

luxury hotels in Lesbos
Agrilia Kratigou, Mytilene, 81100, Greece
8.2
857 reviews
From $215

Guest Review: Perfect five star hotel . Very clean , great food , luxury and very friendly

luxury hotels in Lesbos
Skra 7, Mytilene, 81100, Greece
9.0
520 reviews
From $155

Guest Review: Attitude of the staff towards us was so kind. They were so polite. They tried to do what we wished.

luxury hotels in Lesbos
Boyalik Mahallesi 3198/1, 35930 Çeşme, Turkey
9.1
60 reviews
From $607

Guest Review: Facilities, location, beach, availability of restaurant and beach, quiet place

Other great option in Lesbos

luxury hotels in Lesbos
Efthalou, Mythimna, 81108, GR
7.7
59 reviews
From $76

Guest Review: Location was excellent Staff were excellent Bed was wonderful

Lesbos Luxury Hotels on the Map

Frequently Asked Questions

For a luxurious retreat, consider Mythical Coast Wellness Retreat:BC-9444952 and Reges, a Luxury Collection Resort & Spa, Cesme:BC-5204683. Both hotels offer exquisite spa services, stunning accommodations, and breathtaking views, making them perfect for relaxation and rejuvenation while enjoying the beauty of Lesbos.

Yes! For a romantic getaway, you can stay at Theofilos Paradise Boutique Hotel:BC-273019 or Boyalik Beach Hotel & Spa Cesme:BC-543060. Both offer intimate settings, beautiful designs, and access to serene beaches, creating the ideal atmosphere for couples looking to unwind together.

Food enthusiasts will love staying at D - Resort Ayvalık:BC-1290079 and PEARL ISLAND CHIOS HOTEL & SPA:BC-11607568. These hotels feature exceptional dining options that showcase local flavors and gourmet cuisine, providing an unforgettable culinary experience during your visit to Lesbos.

For families, consider Reges, a Luxury Collection Resort & Spa, Cesme:BC-5204683 and Boyalik Beach Hotel & Spa Cesme:BC-543060. Both hotels offer spacious rooms, kid-friendly amenities, and activities for all ages, ensuring that every family member enjoys their stay on this beautiful island.

Beach lovers should check out Mythical Coast Wellness Retreat:BC-9444952 and Boyalik Beach Hotel & Spa Cesme:BC-543060. Both hotels boast stunning beachfront locations, allowing guests to enjoy sun-soaked days and picturesque sunset views right at their doorstep.

Absolutely! For contemporary design and style, look into Theofilos Paradise Boutique Hotel:BC-273019 and D - Resort Ayvalık:BC-1290079. These hotels feature modern architecture, elegant interiors, and stylish amenities, catering to travelers who appreciate chic aesthetics during their stay.