The 12 Best Luxury Hotels with Spa in Ios (2025)

Nestled along the pristine shores of Manganari, Calilo transcends the traditional resort experience, offering an enchanting escape that feels both intimate and lavish. Here, the soft whispers of the Aegean breeze mingle with the gentle lapping of waves, creating a symphony of tranquility that invites couples and adventurers alike to immerse themselves in a world of exquisite design and natural beauty.

Total Relaxation - Surrender to serenity as you bask by the shimmering pool or on your private beach, where the sun casts golden reflections on crystal-clear waters, inviting you to unwind completely.

Romantic Break - Discover secluded nooks adorned with stunning artworks and breathtaking views, perfect for stolen moments or sunset toasts, all while being enveloped in the warmth of exceptional service.

Chic & Elegant Design - Every corner of Calilo is a testament to artistry, with spaces that feel like living galleries—each suite boasting vast windows framed by the surrounding mountains and thoughtfully curated decor that enchants the senses.

Guest Experiences - Strolling through the unique entrance that feels more like an art installation than a hotel, guests have remarked on the mesmerizing scents of the Mediterranean flora and the delightful surprise of joining the friendly staff at a closing party, where laughter and culinary delights danced together under starlit skies.

Nestled in the enchanting embrace of Ios Chora, Liostasi is a sanctuary where luxury meets the azure waves of the Aegean Sea. Indulge in the exquisite elegance of this boutique hotel, where each detail whispers romance and every corner invites serenity, creating an idyllic backdrop for couples, honeymooners, and adventurous souls alike.

Romantic Escape - With its sweeping sea views and intimate terraces, Liostasi offers an unparalleled romantic atmosphere that enchants couples seeking to celebrate love amidst breathtaking landscapes.

Wellbeing Retreat - Immerse yourself in rejuvenation at our on-site spa, where the gentle scents of natural oils mingle with soft melodies, crafting a tranquil haven ideal for those yearning for relaxation and renewal.

Culinary Delight - Savor the essence of Greek cuisine at Grandma’s Restaurant, where local flavors dance across your palate as you dine under the open sky, accompanied by the soothing sound of waves lapping against the shore.

Guest Experiences - As the sun dipped below the horizon, the alluring aroma of freshly baked bread wafted through the air, beckoning guests to indulge in a delightful breakfast spread. Friendly staff members shared smiles and personalized tips about local treasures, making every moment feel like a cherished memory.

Nestled on the sun-kissed shores of Mylopotas, Levantes Ios Boutique Hotel is a serene escape where elegance meets the vibrant essence of the Aegean. With sweeping sea views and an inviting atmosphere, every moment here feels steeped in luxury and romance, making it the perfect getaway for couples and adventurers alike.

Stunning Sea Views - Bask in breathtaking vistas from your private balcony, where the azure hues of the Aegean blend seamlessly with the warm golden sands below. Each sunset paints a unique masterpiece across the horizon, leaving you spellbound as you sip cocktails by the pool.

Chic and Cozy Accommodations - Each elegantly designed room harmoniously merges ethnic, Mediterranean, and classical styles, offering a sanctuary for relaxation. Luxurious double beds, indulgent bathrooms, and select rooms showcasing private pools provide an intimate retreat tailored for romance and rejuvenation.

Culinary Delights - Start your day with an exquisite breakfast, delivered to your room as the scent of fresh pastries wafts through the air. Enjoy light bites and inventive cocktails at the stylish snack-cocktail bar, where attentive staff ensures every craving is met until the stars begin to twinkle above.

Guest Experiences - As the sound of gentle waves caresses the shore, guests have marveled at the warm hospitality of Dimitris, the bartender, whose attentive service transforms simple cocktails into memorable experiences, often accompanied by laughter echoing under the moonlit sky.

Nestled on the enchanting cliffs of Oia, Oia Sunset Villas invites you to experience the true essence of Cycladic luxury. With sweeping views of the Aegean Sea and sunsets that set the sky ablaze, each villa offers a private sanctuary where modern elegance meets traditional charm, allowing couples and families alike to create unforgettable memories in this breathtaking landscape.

Romantic Retreat - Imagine stepping onto your terrace to find a bubbling hydromassage tub waiting for you, the soft sound of waves below, and the sun dipping into the horizon—it's the ultimate romantic escape, effortlessly blending intimacy with luxurious comfort.

Total Relaxation - Each villa, adorned with arched ceilings and mosaic tiles, exudes a calming ambiance, making it a perfect haven for wellness enthusiasts seeking tranquility after an adventurous day exploring Santorini's hidden gems.

Outstanding Location - Just a leisurely stroll from the vibrant heart of Oia, the villas offer both seclusion and accessibility, letting you enjoy serene moments away from the bustling crowds while being only minutes from local restaurants and shops.

Guest Experiences - Upon arrival, the delightful aroma of traditional Greek delicacies filled the air as guests were welcomed with a charming basket brimming with local products—a lovely touch that made them instantly feel at home, enveloped in the warm hospitality characteristic of their stay.

Nestled in the captivating cliffs of Thólos, Domes Novos Santorini, Autograph Collection invites you to indulge in an oasis of elegance and tranquility. With panoramic views that seem to stretch into eternity, this luxurious retreat is a sanctuary for couples and adventure seekers alike, where every sunset paints the sky with hues of romance and serenity.

Romantic Escape - Immerse yourself in an intimate atmosphere as you unwind on your private terrace, where soft sea breezes mingle with the scent of blooming jasmine, creating an enchanting backdrop for moonlit evenings.

Spa & Relaxation - Pamper your senses at the state-of-the-art spa, where soothing treatments inspired by the island's natural beauty transport you to a realm of pure bliss, leaving you rejuvenated and ready for new adventures.

Outstanding Location - Strategically positioned, the hotel serves as an ideal base for exploring the magic of Santorini. With its own parking area, guests can effortlessly venture out to discover local markets and hidden gems across the island.

Guest Experiences - Guests have marveled at the splendid moments spent savoring breakfast while gazing at breathtaking views—a ritual enhanced by the enticing aroma of freshly baked pastries wafting through the air, making each morning feel like a celebration.

Nestled in the enchanting village of Oia, Santo Pure Oia Suites & Villas invites you to bask in a haven of luxury and tranquility. With breathtaking views of the Aegean Sea and intimate private verandas featuring whirlpool baths, every moment becomes a timeless escape into romance and elegance. Here, lush greenery surrounds chic whitewashed suites, offering an oasis of peace just a stone's throw from the vibrant heart of Santorini.

Romantic Getaway - Each suite is a sanctuary of sophistication, where candlelit evenings can be spent soaking under the stars in your own hot tub, with the gentle sounds of the sea providing a serene soundtrack to your love story.

Spa Retreat - Indulge in rejuvenating treatments at the award-winning spa, where soothing aromas and the soft sound of trickling water create a blissful atmosphere, making it easy to forget the world outside as you surrender to relaxation.

Gastronomic Delights - Savor the essence of modern Greek cuisine at Alios Ilios Restaurant, where each dish tells a story and pairs exquisitely with sunset views that paint the sky in hues of orange and pink, leaving your palate and heart equally satisfied.

Guest Experiences - One guest recalled the delightful surprise of waking up to the scent of fresh pastries wafting through the air during breakfast, while another reveled in the feeling of utter pampering as staff prepared a special birthday cake, adding a personal touch to their unforgettable stay.

Nestled above the enchanting Ammoudi Bay in Oia, Canaves Epitome invites you to experience a sanctuary where romance and luxury intertwine. Here, stunning sunsets melt into the horizon, casting golden hues across your private plunge pool while the gentle sounds of the Aegean create an intimate atmosphere, making every moment feel like a cherished memory.

Infinity Bliss - Take a dip in the infinity-style pool where the seamless blend of water and sky creates a breathtaking backdrop for relaxation and rejuvenation, punctuated by the laughter of friends and the clinking of glasses from nearby cabanas.

Culinary Delights - Savor gourmet breakfasts delivered from a curated menu that tempts your palate with local flavors, while the air is filled with the tantalizing aroma of freshly prepared dishes, making each meal an unforgettable experience.

Serene Wellness Retreat - Immerse yourself in tranquility with daily yoga sessions that awaken your senses, offering a serene escape accompanied by the scent of blooming bougainvillea and the soft rustle of leaves in the breeze.

Guest Experiences - Upon arrival, the friendly staff greeted us with warm smiles, instantly making us feel at home. One evening, we dined under a canopy of stars, where the soft strains of live music mingled with the salty sea air, creating an ambiance so magical that we wished time would stand still.

Nestled on the cliffs of Oia, Santo Mine Oia Suites is a sanctuary where modern luxury meets timeless Greek charm. With each suite offering breathtaking sea views and an intimate atmosphere, this elegant hideaway is the perfect backdrop for unforgettable romantic escapes and tranquil retreats alike.

Total Relaxation - Indulge in serene moments by the stunning outdoor swimming pool, where the horizon melts into a palette of sunset hues. The gentle sound of waves lapping against the rocks below provides a soothing soundtrack as you unwind in this peaceful oasis.

Outstanding Location - Just a leisurely stroll from Katharos Beach and the vibrant heart of Oia, the hotel's enviable location allows guests to explore local treasures while returning to their private haven filled with stunning vistas and contemporary comforts.

Spa Breaks - Experience rejuvenation at its finest with a range of bespoke treatments designed to pamper and revive. Guests have raved about the spa massages that transport them into blissful tranquility, leaving them feeling completely refreshed.

Guest Experiences - Upon arrival, guests are treated to delightful surprises, like a complimentary bottle of wine and fresh fruits, setting the tone for a warm welcome. As the sun sets, the aroma of gourmet dishes wafts through the air, perfectly timed for cocktails delivered just as the sky transforms into a canvas of colors.

Nestled within the enchanting cliffs of Oia, the Andronis Arcadia Hotel is a sanctuary of luxury and tranquility, where azure waves serenade your senses against the backdrop of breathtaking sunsets. Each elegantly designed space whispers intimacy and romance, inviting couples and wanderers alike to indulge in its serene embrace while savoring the exquisite beauty that surrounds them.

Romantic Escape - With private pools in select suites and sweeping sea views, each moment at Andronis Arcadia feels like a scene from a love story, perfect for honeymooners seeking an idyllic retreat.

Gourmet Delights - The on-site Beefbar restaurant tantalizes taste buds with meticulously crafted dishes, featuring local flavors that linger long after the meal, complemented by breakfast spreads that promise to awaken every palate.

Wellness Retreat - Escape into relaxation at the state-of-the-art spa, where soothing scents mingle with tranquil sounds as you unwind through personalized treatments designed to rejuvenate body and soul.

Guest Experiences - One guest relished the delightful surprise of entering a room adorned with romantic touches celebrating their mini-moon; the air was infused with soft floral notes, while the gentle sound of waves provided a comforting soundtrack to their unforgettable stay.

Nestled in the enchanting cliffs of Oia, Elea Resort - Adults Only invites you to retreat into a world where luxury meets serenity. With sweeping views of the Aegean Sea and breathtaking sunsets that paint the sky in vibrant hues, this intimate haven is designed exclusively for those seeking romance and rejuvenation in an idyllic setting.

Outstanding Location - Perched just beyond the bustling heart of Oia, the resort offers a tranquil escape that feels worlds away yet is only a short stroll from charming shops and exquisite dining options. The gentle sound of waves lapping against the shore complements the spectacular vistas, creating a romantic symphony.

Total Relaxation - With two beautifully designed outdoor pools and an infinity pool that seemingly spills into the sea, basking in the sun has never been more delightful. Ample sun loungers await, inviting you to unwind while you sip on expertly crafted cocktails and enjoy light bites inspired by local flavors.

Spa Breaks - Indulge in moments of pure bliss at the resort's serene hammam and hot tub, where tranquility envelops you. The soothing scents of essential oils fill the air, calming your senses as you retreat from the world outside and melt into the luxurious ambiance.

Guest Experiences - From the moment you arrive, you’re treated like royalty—with a warm welcome accompanied by a bottle of wine and a fresh fruit platter. Mornings are magical, as the aroma of freshly brewed coffee wafts through your private patio, where breakfast is elegantly served, allowing you to savor every bite while gazing at the sun rising over the crystal-clear waters.

Perched majestically on the cliffs of Oia, Fanari Villas invites you to immerse yourself in a sanctuary of elegance and tranquility. As the sun dips below the horizon, casting golden hues over the caldera and Thirasia Island, each suite becomes a private oasis of romance, artfully carved into the rock face and adorned with handcrafted treasures. Here, every moment whispers luxury and intimacy, making it the perfect escape for couples and discerning travelers alike.

Romantic Retreat - With breathtaking views from your own terrace, evenings spent under the stars become unforgettable. Imagine a candlelit dinner for two, served al fresco, as the sky transforms into a tapestry of pinks and purples, creating an ambiance that's both intimate and magical.

Wellness Haven - Indulge in rejuvenating treatments that harmonize body and soul, from soothing massages to invigorating sauna sessions. Each carefully curated wellness experience immerses you in a state of total relaxation, allowing you to unwind and reconnect amidst the serene backdrop of Oia's stunning vistas.

Culinary Delight - Savor local cuisine reimagined with a modern flair at our exquisite restaurant. The aroma of fresh ingredients wafts through the air as you sample seasonal dishes, perfectly paired with wines that echo the essence of the land—each bite a testament to the culinary artistry inspired by the island's rich heritage.

Guest Experiences - A couple found themselves enchanted by the complimentary drinks awaiting them in their suite, an unexpected touch that made their arrival feel special. As they sipped wine on their balcony, the tranquil sounds of waves lapping against the cliffs mingled with laughter from nearby diners, wrapping them in the warm embrace of Oia's vibrant atmosphere.

Nestled on the threshold of Santorini's breathtaking caldera, Art Maisons Oia Castle offers an idyllic sanctuary where contemporary elegance entwines with traditional Cycladic charm. As the sun dips below the horizon, painting the sky in hues of orange and pink, your private terrace becomes the perfect backdrop for capturing romantic moments that last a lifetime.

Outstanding Location - Perched dramatically above the Aegean Sea, each suite provides unrivaled views that transform every sunset into a captivating spectacle. The soothing sound of waves crashing against the cliffs creates a serene soundtrack to your stay.

Total Relaxation - Indulge in the luxurious simplicity of our accommodations, where minimalist design meets plush comfort, inviting you to unwind fully amidst the tranquil atmosphere. Your suite envelops you in a cocoon of peace, accented by soft linens and gentle lighting.

Intimate - With just a handful of exquisitely designed suites, Art Maisons Oia Castle fosters a sense of intimacy that makes you feel as though the stunning landscapes are yours alone. The peaceful ambiance invites quiet conversations and stolen glances, perfect for those seeking a romantic escape.

Guest Experiences - Guests often reminisce about the thoughtful details: a staff member presenting a breakfast tray filled with local delights, the aroma of freshly baked pastries wafting through the air, or the feeling of warm sunlight filtering through the curtains as they sip coffee on their terrace while watching the world wake up.