The 10 Best Luxury Hotels with Spa in Ermoupoli (2025)

Nestled on the enchanting island of Syros, Ermoupoli is a captivating blend of neoclassical architecture and vibrant culture, characterized by its bustling harbour and the iconic Apollon Theatre. As you wander through its charming streets, you'll encounter an array of artisanal shops, inviting cafes, and the aromatic allure of local cuisine. The city's stunning vistas, particularly from the picturesque neighborhood of Ano Syros, create an idyllic backdrop for a luxurious getaway. In this enchanting setting, Ermoupoli luxury hotels with spa facilities redefine opulence, offering exclusive retreats that cater to discerning travelers. The elegant Hotel Ploes, with its rich history and breathtaking sea views, provides a perfect sanctuary for relaxation. Meanwhile, Castro Hotel Syros combines modern sophistication with traditional charm, making it a favored choice for those seeking a unique experience. For an extraordinary stay, Odara, part of the Autograph Collection, immerses guests in the island's exquisite beauty and refined comfort. Embark on your journey to discover these gems and explore our curated collection to begin planning your dream escape.

Top Luxury Hotels in Ermoupoli

luxury hotels in Ermoupoli

Hotel Ploes

Hotel
Apollonos 2, Ermoupoli, 84100, Greece

Nestled in the heart of Ermoupoli, Hotel Ploes is an exquisite blend of timeless elegance and modern luxury, housed within a meticulously restored Neoclassical mansion from the early 19th century. As you step inside, the scent of freshly brewed coffee mingles with the sea air, inviting you to unwind in a space where every detail whispers sophistication and romance.

Romantic Retreat - With views stretching over the shimmering Aegean Sea, the hotel’s intimate settings—like the serene outdoor café—provide a perfect backdrop for couples seeking a memorable escape. Here, candlelit evenings transform into cherished memories under a starlit sky.

Chic Accommodations - Each room tells its own story, featuring high ceilings adorned with hand-painted murals and sunlight dancing off Venetian chandeliers, creating an atmosphere of opulent comfort. Luxurious marble bathrooms beckon with indulgent spa baths, offering a personal oasis away from the world.

Culinary Delights - Mornings at the terrace become a sensory feast, as the aroma of fresh pastries fills the air while guests savor a delightful breakfast that includes local ingredients and crafted dishes like poached egg avocado toast—all enjoyed with picturesque views of palm trees and the gentle lapping waves.

Guest Experiences - As I settled on my balcony with a glass of sparkling wine, the sounds of chirping starlings danced through the air, merging with the laughter from the nearby café. Each sip was a toast to the warm hospitality as staff members personally knew my name, adding a cozy touch to this elegant stay.

luxury hotels in Ermoupoli

Castro Hotel Syros

Hotel
12 Kalomenopoulou, Ermoupoli, 84100, Greece

Nestled in the vibrant heart of Ermoupoli, Castro Hotel Syros offers an enchanting escape where modern elegance dances harmoniously with timeless charm. Imagine sipping a perfectly brewed cup of coffee on your private terrace as the gentle sea breeze carries whispers of history and romance through the air, inviting you to explore the captivating beauty of Syros Island.

Romantic Retreat - With its chic decor and intimate ambiance, each room at Castro Hotel is a sanctuary designed for couples, offering a perfect blend of luxury and comfort that sets the stage for unforgettable moments together.

Total Relaxation - Indulge in tranquility at the hotel’s spa, where soothing aromas and soft music create a haven of peace, complemented by complimentary shoulder massages that leave guests feeling refreshed and renewed after a day of exploration.

Outstanding Location - Situated just a stone's throw from Asteria Beach and local attractions, the hotel provides easy access to the vibrant life of Ermoupoli while maintaining a serene atmosphere, allowing guests to retreat to their chic oasis after a day of adventure.

Guest Experiences - Visitors have noted the delightful touch of fresh flowers embellishing the rooms, along with the warm smiles of staff who make it a point to remember your name and preferences—a small but meaningful detail that adds a personal touch to your stay.

luxury hotels in Ermoupoli

Odera, Tinos, Autograph Collection

Hotel
Vourni Beach, Kionia, 84200, Greece

Nestled along the sun-drenched shores of Kionia, Odera, Tinos, Autograph Collection invites you to indulge in an oasis where modern luxury meets timeless Greek charm. With its breathtaking sea views and a serene private beach just steps away, this exquisite retreat envelops guests in romance and tranquility, making it the perfect getaway for couples and seekers of sophistication.

Total Relaxation - Dive into unparalleled relaxation at our stunning outdoor swimming pool, where the sun casts playful reflections on glistening waters. Recline on elegant loungers surrounded by lush gardens, sipping handcrafted cocktails as the gentle sounds of waves create the perfect backdrop for your escape.

Outstanding Location - With the pristine sands of Vourni Beach a leisurely stroll away, every corner of this idyllic location beckons exploration. Guests can meander through local markets or discover hidden coves, all while soaking in the breathtaking vistas that define this coastal paradise.

Chic Dining Experience - Savor culinary excellence at our on-site restaurant, where each dish is a celebration of Greek and Mediterranean flavors. From vibrant local produce to aromatic herbs, the menu reflects the essence of Tinos, complemented by an ambiance that transforms dining into an artful experience under the stars.

Guest Experiences - Amidst the tranquil atmosphere, one guest found joy in the early morning aromas wafting from the kitchen, mingling with the salty breeze. As they enjoyed freshly brewed coffee on their balcony, the stunning sunrise painted the sky in hues of pink and gold, setting the tone for a dreamy day ahead.

luxury hotels in Ermoupoli

Katikies Mykonos - The Leading Hotels of the World

Hotel
Agios Ioannis Mykonos, 84600, Greece

Nestled in the serene embrace of Agios Ioannis, Katikies Mykonos is a sanctuary where Cycladic beauty melds seamlessly with contemporary elegance. Here, the sun-kissed terraces offer uninterrupted views of the Aegean Sea, creating an intimate setting for couples and luxury seekers alike, whether basking by the infinity pool or savoring gourmet cuisine under the stars.

Romantic Escape - Revel in the charm of private terraces and outdoor jetted tubs, where moments become memories against stunning sea vistas, ideal for honeymoons or romantic getaways that beckon you to lose track of time together.

Culinary Delights - Indulge your palate at Botrini's Mykonos, where the award-winning creations of Chef Ettore Botrini come alive amidst a backdrop of azure waters and breathtaking sunsets; each dish is a masterpiece crafted from the freshest local ingredients, inviting guests on a sensory journey of flavors.

Wellness Retreat - Embrace tranquility at the hotel’s spa center, where soothing aromas of essential oils fill the air as skilled therapists guide you through rejuvenating treatments; unwind in luxurious surrounds designed for total relaxation, allowing body and mind to harmonize perfectly amidst the sounds of gentle waves.

Guest Experiences - As the sun dipped below the horizon, a couple found themselves enchanted by the delightful breakfast served by attentive staff—each morning brought a different selection of local delicacies, paired with the sweet scent of freshly brewed coffee wafting through the air, ensuring their days began in pure bliss.

luxury hotels in Ermoupoli

The Coast Bill & Coo -The Leading Hotels of the World

Hotel
Agios Ioannis, Agios Ioannis Mykonos, 84600, Greece

Nestled along the pristine shores of Agios Ioannis, The Coast Bill&Coo offers a sanctuary for adults seeking romance and relaxation. Here, every moment evokes a sense of intimacy, from the gentle whispers of waves lapping against the beach to the warm glow of sunset reflecting on chic, private terraces adorned with plunge pools and jacuzzis.

Total Relaxation - Rejuvenate your spirit in a serene oasis, where soft breezes carry the scent of saltwater and blooming bougainvillea, and each suite invites you to unwind in luxe surroundings with breathtaking views.

Romantic Break - Immerse yourself in an enchanting escape designed for lovers, featuring secluded beachfront dining under starlit skies, where every meal is accompanied by the soft sound of surf and the clink of fine glassware.

Spa Breaks - Indulge in bespoke wellness treatments that promise tranquility, as skilled therapists use aromatic oils to melt away tension, enveloping you in a cocoon of soothing scents amidst the sounds of nature.

Guest Experiences - One guest recounted how they awoke to the melodic call of sea birds, their morning coffee complemented by the fragrant aroma of fresh pastries wafting from the restaurant, making the early hours feel like a luxurious treat.

luxury hotels in Ermoupoli

DeLight Boutique Hotel - Small Luxury Hotels of the World

Hotel
Agios Ioannis, Agios Ioannis Mykonos, 84600, Greece

Nestled in the serene embrace of Agios Ioannis, the DeLight Boutique Hotel offers an idyllic sanctuary where modern luxury meets the captivating beauty of the Aegean Sea. With stunning views of the sacred Delos Island, each moment spent here feels like a private escape into a world of elegance and tranquility, perfect for romantic retreats or rejuvenating getaways.

Outstanding Location - Perched above the shimmering waters, guests relish breathtaking sunsets that paint the horizon in hues of orange and pink while the gentle sound of waves creates a soothing soundtrack to their stay.

Intimate Spa Breaks - Indulge in personalized wellness experiences, with calming massages available on request, ensuring each guest feels rejuvenated as they unwind amidst the chic décor and soft ambient music that fills the air.

Gourmet Culinary Experiences - At DeLight, savor a morning feast featuring both Greek and American delicacies, where the aroma of fresh pastries mingles delightfully with the scent of the sea breeze, setting the tone for a perfect day of relaxation.

Guest Experiences - One guest recalled the sensation of slipping into plush bathrobes after a day by the pool, as the friendly staff anticipated her every need, even remembering her favorite cocktail, which arrived with a flourish just as she settled in for the sunset.

luxury hotels in Ermoupoli

Noima Boutique Hotel Mykonos

Hotel
Agios Ioannis Diakoftis, Agios Ioannis Mykonos, 84600, Greece

Nestled in the serene embrace of Agios Ioannis, Noima Boutique Hotel Mykonos beckons with its luxurious charm and breathtaking vistas of the Aegean Sea. Just moments from the golden sands of Agios Ioannis Beach, this intimate sanctuary inspires romance and relaxation, inviting couples and wellness seekers alike to indulge in a unique blend of modern elegance and Greek hospitality.

Romantic Getaway - With thoughtfully designed spaces that exude intimacy, each room offers a private escape, complete with plush furnishings, stunning sea views, and inviting terraces that whisper secrets of sunset cocktails under the stars.

Total Relaxation - Guests can unwind in style as they enjoy invigorating spa treatments or take a leisurely dip in the hotel’s luxurious pool, all while soaking in the tranquil atmosphere enriched by gentle waves lapping at the shore nearby.

Culinary Delights - Mornings at Noima are a sensory delight as guests savor an à la carte breakfast infused with local flavors, where the aroma of freshly brewed coffee mingles with the sweet scent of pastries, making each bite a celebration of Greek culinary artistry.

Guest Experiences - One guest shared how the staff's warm gestures transformed their stay into a homely retreat; from the fragrant blooms adorning their room upon arrival to the soft background music that accompanied their morning meals, every detail felt like a personal touch meant just for them.

luxury hotels in Ermoupoli

Domes Noruz Mykonos

Hotel
Mykonos, Agios Stefanos, Mikonos, 84600, Greece

Nestled on the sun-kissed shores of Mykonos, Domes Noruz Mykonos exudes a sense of serene luxury that invites you to unwind in its elegant embrace. With stunning views and modern design elements that harmoniously blend with the island's natural beauty, this idyllic spot is perfect for couples seeking romance or friends embarking on an unforgettable escape.

Romantic Break - With secluded terraces overlooking shimmering waters, each moment feels like a private celebration of love, whether lounging by the infinity pool or sipping cocktails under a starlit sky.

Spa Breaks - Indulge in a sanctuary of tranquility at the hotel's spa, where soothing scents of essential oils mingle with calming sounds of gentle waves, crafting an experience that rejuvenates both body and soul.

Boutique - Each corner of this beautiful boutique hotel tells a story through its chic design and handpicked artworks, creating an inspiring backdrop for your holiday that feels fresh yet timeless.

Guest Experiences - As you step into the lobby, the delicate scent of jasmine wafts through the air, welcoming you into a stylish yet inviting space. Guests often reminisce about the friendly staff who not only remembered their names but also anticipated their favorite drinks by the pool, making them feel like cherished friends rather than just visitors.

luxury hotels in Ermoupoli

Mykonos Grand Hotel & Resort

Hotel
Agios Ioannis, Agios Ioannis Mykonos, 84600, Greece

Nestled along the stunning Agios Ioannis Beach, Mykonos Grand Hotel & Resort invites you to indulge in an intimate escape where every moment is steeped in luxury and serenity. With its breathtaking views of Delos Island and meticulously designed spaces that echo the charm of Cycladic architecture, this boutique retreat is a sanctuary for romantics and wellness seekers alike.

Culinary Delights - Savor an exquisite culinary journey as the ocean breeze carries the enticing aromas of fresh seafood and expertly grilled specialties from the open-air dining room—a place where each meal becomes a cherished moment against a backdrop of panoramic sea views.

Wellness Oasis - Rejuvenate your senses at Althea Spa Centre, where traditional Greek techniques meet modern indulgence. Here, the air is infused with calming essential oils, offering a blissful retreat after a day of exploration or sun-soaked relaxation by the pool.

Stunning Seascapes - Step onto your private balcony and let the mesmerizing hues of dawn and dusk paint the sky over the Aegean Sea. The soothing sound of waves lapping against the shore creates an enchanting symphony that accompanies your every waking moment.

Guest Experiences - Many guests relished their morning rituals as the rich scent of freshly brewed coffee wafted through the air, mingling with the aroma of baked pastries; enjoying breakfast on expansive terraces while watching the colorful spectacle of seagulls dancing over the water became a daily highlight.

luxury hotels in Ermoupoli

Saint John Hotel Villas & Spa

Resort
Agios Ioannis, Agios Ioannis Mykonos, 84600, Greece

Nestled along the stunning shores of Agios Ioannis, Saint John Hotel Villas & Spa embodies an oasis of luxurious tranquility. With its infinity pool seamlessly merging with the Aegean Sea and elegantly designed rooms offering breathtaking views, this resort is a romantic escape where each moment feels like a cherished memory waiting to unfold.

Total Relaxation - Indulge in the Aphrodite Spa & Beauty Center, where serenity reigns supreme. Immerse yourself in lavish treatments within tranquil treatment rooms, savoring the soothing aromas and gentle sounds that transport you to a world of blissful relaxation.

Romantic Break - Whether enjoying a candlelit dinner under the stars or strolling hand-in-hand along the private beach at sunset, every corner of this hotel sets the perfect stage for romance. The gentle sound of waves lapping against the shore creates a soundtrack to your love story.

Outstanding Location - With Mykonos Town just a short drive away, you can explore the vibrant local culture and return to your serene retreat with ease. Each morning greets you with spectacular views of sun-drenched waters, inviting you to bask in the warmth of the Grecian sun.

Guest Experiences - One guest marveled at the unexpected attentiveness of the staff as they captured family moments by the picturesque bridge over the pool, while another rave about the delightful cocktails served at the Breeze Pool Bar, with the sweet scent of citrus lingering in the air.

Best Luxury Hotels that guests love in Ermoupoli

luxury hotels in Ermoupoli
Agios Ioannis, Agios Ioannis Mykonos, 84600, Greece
9.2
1123 reviews
From $594

Guest Review: I will start with the reception staff. We received a very warm welcome. Staff members across property were polite, always ready to help and courteous. My room was an awesome room with a balcony facing sea which enhances the overall experience. The view was splendid. Room had excellent facilities for international customers. Like usb charging, c type charging, universal sockets are some of the things to name. The hotel has 2 big swimming pools, kids pool, spa, a nice private beach with deck and shore both. It also has a chapel in the campus. They have lovely sun beds near pool as well as at private beach. You can just relax there. Best thing is they server food and drinks at private beach, pool side or on the open sun deck. Private beach is quite beautiful facing west. We took a stroll around the beach and enjoyed being there seeing the lovely sunset peacefully without any crowd being there. They have a nice and small bridge to cross the pool and that gives an awesome view to the pool. This point was quite picturesque and we did click some lovely pictures there. While me and my wife were clicking pictures my son who will jump into pool water the moment he sees it, was taken care of by hotel staff, they played with him, kept him engaged in activities so that we could click pictures. This was such a splendid gesture. Without their help it was not possible to click pictures so peacefully. Coming to restaurants, they have variety of restaurants and bar available. They server excellent and authentic Greek cuisines. We really wanted to try that and they served us with that. I enjoyed my stay. Yo enjoy all facilities it took us an entire 1.5 days. We didn’t step out for anything. It is a little Mykonos’s within Mykonos. I enjoyed being there and will always prefer to stay here whenever I visit Mykonos.

luxury hotels in Ermoupoli
Agios Ioannis, Agios Ioannis Mykonos, 84600, Greece
9.5
270 reviews
From $516

Guest Review: Everything was fantastic! We did pay for a high end room. Food was very good although we only had the breakfast (lots of options greek and american) which was included, plus a few delicious margarita pizzas by the pool in the afternoon. The staff, the view, the room, and did I say staff?, because they were tremendous. The restaurant/pool crew of Helen, George, Manos (sp?), Giannis, Alejandros (sp?) were the best I've ever experienced. Mini market/ATM/Bus stop directly across the street, very convenient.

luxury hotels in Ermoupoli
Agios Ioannis, Agios Ioannis Mykonos, 84600, Greece
9.7
246 reviews
From $584

Guest Review: The buffet had a wide variety of Grecian delights.The presentation made you want to try everything, and it was delicious. We looked forward to breakfast.

Ermoupoli Luxury Hotels on the Map

Frequently Asked Questions

For a lavish experience, consider Saint John Hotel Villas & Spa and Katikies Mykonos - The Leading Hotels of the World. Both offer exceptional spa services, designed to pamper you after a day exploring the enchanting streets of Ermoupoli.

For families seeking relaxation and indulgence, Domes Noruz Mykonos and Mykonos Grand Hotel & Resort provide luxurious accommodations along with exquisite spa facilities. These hotels ensure both adults and children have a memorable stay.

Yes! DeLight Boutique Hotel - Small Luxury Hotels of the World and The Coast Bill & Coo -The Leading Hotels of the World are perfect for couples looking for romance and relaxation. Enjoy serene spa treatments while soaking in the stunning views of the Aegean Sea.

If you're a design enthusiast, check out Odera, Tinos, Autograph Collection and Noima Boutique Hotel Mykonos. These boutique hotels combine stylish interiors with luxurious spa services, providing a unique and indulgent experience in Ermoupoli.

For travelers on a budget but still craving luxury, Castro Hotel Syros and Hotel Ploes offer affordable rates alongside excellent spa amenities. Enjoy a refined experience without breaking the bank!

Consider Saint John Hotel Villas & Spa and Katikies Mykonos - The Leading Hotels of the World for breathtaking views combined with top-notch spa experiences. Unwind at these stunning properties that showcase the beauty of Ermoupoli.