21 Best Luxury Hotels with Spa in Panama City

Hotel La Compañía Casco Antiguo

Hotel

Avenida A, Esquina Calle 8, Casco Antiguo, Panama City, Panama

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Romantic Retreat
Culinary Delights
Historic Elegance

10 Baths 447.78 ft²

Sofitel Legend Casco Viejo, Panama City

Hotel

Calle Primera Oeste San Felipe Casco Viejo, 843 Panama City, Panama

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Outstanding Location
Total Relaxation
Spa Breaks

18 Baths 814.02 ft²

The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City

Hotel

Santa Maria Boulevard, Panama City, Panama

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Golfing Paradise
Culinary Delights
Wellness Retreat

7 Baths 881.1 ft²

Central Hotel Panama Casco Viejo

Hotel

Casco Antiguo, Avenida Central calle 5ta, Panama City, Panama

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Historic Charm
Culinary Delights
Wellness Retreat

8 Baths 382.89 ft²

JW Marriott Panama

Hotel

Calle Punta Colon, Punta Pacífica, 0833-00321 Panama City, Panama

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Spectacular Views
Lush Infinity Pool
Culinary Journeys

10 Baths 668.44 ft²

Bristol Panama, a Registry Collection Hotel

Hotel

Calle Aquilino de la Guarida, Bella Vista, 0833-00321 Panama City, Panama

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Total Relaxation
Culinary Delights
Outstanding Location

7 Baths 610.47 ft²

The Westin Panama

Hotel

Avenida la Rotonda Costa del Este, 0000 Panama City, Panama

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Romantic Retreat
Spa Sanctuary
Culinary Delights

5 Baths 622.15 ft²

Waldorf Astoria Panama

Hotel

47th Street & Uruguay Street, Bella Vista, 00000 Panama City, Panama

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Culinary Delights
Spa & Relaxation
Outstanding Location

1 Baths 611.75 ft²

Megapolis Hotel Panama

Hotel

Avenida Balboa Boulevard Elhayek , 0000 Panama City, Panama

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Outstanding Location
Spa Breaks
Romantic Escape

6 Baths 1011.81 ft²

Sortis Hotel, Spa & Casino, Autograph Collection

Hotel

Obarrio calle 56 y 57, Bella Vista, Panama City, Panama

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Spa Retreat
Culinary Delights
City Explorations

8 Baths 943.19 ft²

Hilton Panama

Hotel

Av. Balboa con calle Aquilino de la Guardia, Bella Vista, 0000 Panama City, Panama

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Total Relaxation
Outstanding Location
Culinary Delights

1 Baths 615.93 ft²

W Panama

Hotel

Calle 50 and Aquilino de la Guardia, Bella Vista, 80809 Panama City, Panama

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City Style
Total Relaxation
Outstanding Location

2 Baths 816.71 ft²

Hotel Las Americas Golden Tower Panamá

Hotel

Avenida Balboa con Calle 53 esquina, Marbella, Panama, 587 Panama City, Panama

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Outstanding Location
Spa Breaks
Romantic Getaway

5 Baths 561.87 ft²

Gran Evenia Panamá Hotel

Hotel

Calle Eusebio A. Morales Esquina Calle Augusto Samuel Boyd-Urb El Cangrejo, Bella Vista, Panama City, Panama

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Romantic Break
Spa Breaks
City Style

13 Baths 479.41 ft²

Sheraton Grand Panama

Hotel

Vía Israel y Calle 77 San Francisco, 0819-05896 Panama City, Panama

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Spa Retreats
Culinary Delights
Exceptional Service

5 Baths 365.97 ft²

Le Meridien Panama

Hotel

Calle Uruguay y Avenida Balboa, Bella Vista, NA Panama City, Panama

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Total Relaxation
Outstanding Location
Chic

7 Baths 202.98 ft²

Ramada Plaza by Wyndham Panama Punta Pacifica

Hotel

Vía Israel y Calle 71 San Francisco, Panama City, Panama

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Total Relaxation
Outstanding Location
Romantic Break

4 Baths

Hotel Dann Carlton Panama

Hotel

Aquilino de la Guardia y calle 52, Bella Vista, 0830 Panama City, Panama

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Outstanding Location
Total Relaxation
Spa Breaks

2 Baths 344.45 ft²

Decapolis Hotel Panama City

Hotel

Avenida Balboa-Multicentro, 0833-0293 Panama City, Panama

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City Style
Romantic Break
Spa Breaks

10 Baths 484.38 ft²

Best Western Plus Panama Zen Hotel

Hotel

Vía Argentina ( entrando por el restaurante “El Trapiche”) y Calle Gaspar Hernandez , Corregimiento El Cangrejo, Sector Bellavista, Bella Vista, Panama City, Panama

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Romantic Retreat
Outstanding Location
Wellness Oasis

1 Baths 370.28 ft²

The Buenaventura Golf & Beach Resort, Autograph Collection

Resort

340 Calle 3ra,Buenaventura, Playa Blanca, 00000 Río Hato, Panama

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Romantic Getaway
Total Relaxation
Beach Life

13 Baths 1001.05 ft²

For a lavish experience, consider Sofitel Legend Casco Viejo, Panama City and The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City. Both offer luxurious spa services alongside stunning accommodations, perfect for relaxation after exploring the city's vibrant culture.

Couples will adore Waldorf Astoria Panama for its elegant ambiance and world-class dining, as well as JW Marriott Panama, which features breathtaking views and a serene spa. These hotels create the perfect romantic retreat in Panama City.

Yes! Hilton Panama and The Westin Panama offer family-friendly amenities alongside relaxing spa experiences. Kids can enjoy various activities while parents unwind at the spa, making it a great choice for families traveling to Panama City.

For a unique stay, check out Central Hotel Panama Casco Viejo, known for its charming design and spa offerings, or Sortis Hotel, Spa & Casino, Autograph Collection, where you can indulge in upscale treatments while enjoying the vibrant local scene.

Food enthusiasts will love Bristol Panama, a Registry Collection Hotel for its exceptional dining options and The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City, which provides gourmet cuisine paired with a luxurious spa experience. Both ensure a delightful culinary journey.

Certainly! Explore Hotel La Compania, In The Unbound Collection By Hyatt, known for its historic charm and modern spa services, or Central Hotel Panama Casco Viejo, blending history with luxury amenities, creating a truly memorable stay.