The 11 Best Luxury Family Hotels in The Keys (2026)

Top Luxury Family Hotels The Keys

Cheeca Lodge & Spa

Cheeca Lodge & Spa

Resort
81801 Overseas Highway Mile Marker 82, Islamorada, FL 33036, USA
  • Tropical Escape
  • Gourmet Indulgence
  • Wellness Retreat
12 Baths 642.47 ft²
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

Resort
97450 Overseas Highway, Key Largo, FL 33037, USA
  • Romantic Getaway
  • Spa Indulgence
  • Adventurous Escapades
17 Baths 797.8 ft²
Isla Bella Beach Resort & Spa - Florida Keys

Isla Bella Beach Resort & Spa - Florida Keys

Resort
1 Knights Key Boulevard MM47, Marathon, FL 33050, USA
  • Beach Life
  • Spa Breaks
  • Culinary Delights
13 Baths 769.62 ft²
Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club

Hotel
58182 Overseas Hwy,Marathon FL 3305, Marathon, FL 33050, USA
  • Romantic Retreat
  • Gastronomic Delights
  • Intimate Surroundings
9 Baths 655.06 ft²
Hilton Key West Resort & Marina

Hilton Key West Resort & Marina

Resort
5950 Peninsular Ave, Key West, FL 33040, USA
  • Romantic Retreat
  • Waterfront Dining
  • Active Adventures
12 Baths 473.62 ft²
The Perry Hotel & Marina Key West

The Perry Hotel & Marina Key West

Resort
7001 Shrimp Rd, Key West, 33040, USA
  • Romantic Getaway
  • Culinary Delights
  • Adventure Awaits
3 Baths 394.42 ft²
Santa Maria Suites Resort

Santa Maria Suites Resort

Resort
1401 Simonton Street, Downtown Key West, Key West, FL 33040, USA
  • Romantic Retreat
  • Total Relaxation
  • Outstanding Location
9 Baths 889.1 ft²
Ocean Key Resort & Spa, a Noble House Resort

Ocean Key Resort & Spa, a Noble House Resort

Resort
Zero Duval, Downtown Key West, Key West, FL 33040, USA
  • Romantic Escape
  • Total Relaxation
  • Culinary Delights
1 Baths 633.42 ft²
JW Marriott Marco Island Beach Resort

JW Marriott Marco Island Beach Resort

Resort
400 South Collier Boulevard, Marco Island, FL 34145, USA
  • Total Relaxation
  • Romantic Break
  • Beach Life
7 Baths 398.26 ft²
Holiday Inn Club Vacations Sunset Cove Resort

Holiday Inn Club Vacations Sunset Cove Resort

Resort
571 West Elkcam Circle, Marco Island, FL 34145, USA
  • Romantic Retreat
  • Beach Life
  • Wellbeing
4 Baths 1716.85 ft²
Naples Bay Resort and Marina

Naples Bay Resort and Marina

Resort
1500 5th Avenue South, Naples, FL 34102, USA
  • Romantic Getaway
  • Spa & Relaxation
  • Outdoor Adventures
22 Baths 1147.89 ft²

Best Luxury Hotels that guests love in The Keys

Hilton Key West Resort & Marina
5950 Peninsular Ave, Key West, FL 33040, United States of America
8.5
1206 reviews
From $276
Santa Maria Suites Resort
1401 Simonton Street, Downtown Key West, Key West, FL 33040, United States of America
9.3
681 reviews
From $475
Grassy Flats Resort & Beach Club
58182 Overseas Hwy,Marathon FL 3305, Marathon, FL 33050, United States of America
8.8
622 reviews
From $392

Other great option in The Keys

Marlin Bay Resort & Marina Managed by Elite Alliance Hospitality
3800 Gulfview Avenue, Marathon, 33050, US
10.0
2 reviews
From $1593

Frequently Asked Questions

For a family-friendly stay in The Keys, consider Cheeca Lodge & Spa with its diverse activities and kids' club, or Isla Bella Beach Resort & Spa - Florida Keys, which offers spacious rooms and a fantastic beachfront. Both resorts ensure that families can relax while enjoying fun-filled amenities.

If you're seeking opulence, check out JW Marriott Marco Island Beach Resort known for its stunning beachfront and exquisite dining options, and Ocean Key Resort & Spa, a Noble House Resort, famed for its luxurious spa services and breathtaking sunset views. These hotels redefine luxury in The Keys.

Yes! For a romantic getaway, look into The Perry Hotel & Marina Key West ideal for couples seeking sophisticated comfort, and Santa Maria Suites Resort, where intimate suites offer privacy and elegance. Both evoke the perfect setting for lovebirds.

Travelers on a budget should explore Holiday Inn Club Vacations Sunset Cove Resort, an IHG Hotel for great family amenities at a reasonable price, or Grassy Flats Resort & Beach Club, which combines comfortable accommodations with an excellent location without breaking the bank.

For stunning vistas, Oceans Edge Key West offers gorgeous waterfront scenery, while Playa Largo Resort & Spa, Autograph Collection boasts unparalleled ocean views from its rooms and pools. Both are perfect for travelers who appreciate beautiful sights.

Absolutely! Ocean Key Resort & Spa, a Noble House Resort provides a chic boutique experience perfect for couples, while {Ocean Key Resort & Spa, a Noble House Resort:BC-56532} offers an intimate vibe with romantic dining options and a serene spa, making them ideal escapes for two.