The 20 Best Luxury Hotels in Panama City (2026)

Top Luxury Hotels Panama City

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

Hotel
Avenida A, Esquina Calle 8, Casco Antiguo, Panama City, Panama
• View on map
  • Romantic Retreat
  • Culinary Delights
  • Historic Elegance
10 Baths 447.78 ft²
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Hotel
Calle Primera Oeste San Felipe Casco Viejo, 843 Panama City, Panama
• View on map
  • Outstanding Location
  • Total Relaxation
  • Spa Breaks
18 Baths 814.02 ft²
The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City

Hotel
Santa Maria Boulevard, Panama City, Panama
• View on map
  • Golfing Paradise
  • Culinary Delights
  • Wellness Retreat
7 Baths 881.1 ft²
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Hotel
Casco Antiguo, Avenida Central calle 5ta, Panama City, Panama
• View on map
  • Historic Charm
  • Culinary Delights
  • Wellness Retreat
8 Baths 382.89 ft²
American Trade Hotel

American Trade Hotel

Hotel
Plaza Herrera, Casco Viejo, 00000 Panama City, Panama
• View on map
  • Romantic Escape
  • Culinary Delights
  • Historic Charm
8 Baths 488.41 ft²
JW Marriott Panama

JW Marriott Panama

Hotel
Calle Punta Colon, Punta Pacífica, 0833-00321 Panama City, Panama
• View on map
  • Spectacular Views
  • Lush Infinity Pool
  • Culinary Journeys
10 Baths 668.44 ft²
La Concordia Boutique Hotel

La Concordia Boutique Hotel

Hotel
Casco Antiguo, Ciudad de Panamá, Panama City, Panama
• View on map
  • Romantic Retreat
  • Cultural Exploration
  • Wellbeing Oasis
7 Baths 1493.49 ft²
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

Hotel
Calle Aquilino de la Guarida, Bella Vista, 0833-00321 Panama City, Panama
• View on map
  • Total Relaxation
  • Culinary Delights
  • Outstanding Location
7 Baths 610.47 ft²
The Westin Panama

The Westin Panama

Hotel
Avenida la Rotonda Costa del Este, 0000 Panama City, Panama
• View on map
  • Romantic Retreat
  • Spa Sanctuary
  • Culinary Delights
5 Baths 622.15 ft²
Waldorf Astoria Panama

Waldorf Astoria Panama

Hotel
47th Street & Uruguay Street, Bella Vista, 00000 Panama City, Panama
• View on map
  • Culinary Delights
  • Spa & Relaxation
  • Outstanding Location
1 Baths 611.75 ft²
Megapolis Hotel Panama

Megapolis Hotel Panama

Hotel
Avenida Balboa Boulevard Elhayek , 0000 Panama City, Panama
• View on map
  • Outstanding Location
  • Spa Breaks
  • Romantic Escape
6 Baths 1011.81 ft²
Sortis Hotel, Spa & Casino, Autograph Collection

Sortis Hotel, Spa & Casino, Autograph Collection

Hotel
Obarrio calle 56 y 57, Bella Vista, Panama City, Panama
• View on map
  • Spa Retreat
  • Culinary Delights
  • City Explorations
8 Baths 943.19 ft²
Hilton Panama

Hilton Panama

Hotel
Av. Balboa con calle Aquilino de la Guardia, Bella Vista, 0000 Panama City, Panama
• View on map
  • Total Relaxation
  • Outstanding Location
  • Culinary Delights
1 Baths 615.93 ft²
W Panama

W Panama

Hotel
Calle 50 and Aquilino de la Guardia, Bella Vista, 80809 Panama City, Panama
• View on map
  • City Style
  • Total Relaxation
  • Outstanding Location
2 Baths 816.71 ft²
Hotel Las Americas Golden Tower Panamá

Hotel Las Americas Golden Tower Panamá

Hotel
Avenida Balboa con Calle 53 esquina, Marbella, Panama, 587 Panama City, Panama
• View on map
  • Outstanding Location
  • Spa Breaks
  • Romantic Getaway
5 Baths 561.87 ft²
Gran Evenia Panamá Hotel

Gran Evenia Panamá Hotel

Hotel
Calle Eusebio A. Morales Esquina Calle Augusto Samuel Boyd-Urb El Cangrejo, Bella Vista, Panama City, Panama
• View on map
  • Romantic Break
  • Spa Breaks
  • City Style
13 Baths 479.41 ft²
Riu Plaza Panamá

Riu Plaza Panamá

Hotel
Calle 50 con 53 Este, Marbella, Bella Vista, 0000 Panama City, Panama
• View on map
  • City Style
  • Total Relaxation
  • Foodies
12 Baths 773.04 ft²
Marriott Panama Hotel - Albrook

Marriott Panama Hotel - Albrook

Hotel
Albrook Mall, Roosevelt Avenue, Panama City, Panama
• View on map
  • Outstanding Location
  • Romantic Break
  • Spa Breaks
2 Baths 439.79 ft²
Sheraton Grand Panama

Sheraton Grand Panama

Hotel
Vía Israel y Calle 77 San Francisco, 0819-05896 Panama City, Panama
• View on map
  • Spa Retreats
  • Culinary Delights
  • Exceptional Service
5 Baths 365.97 ft²
Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre

Hotel
Calle Colombia y Avenida 3ra. A Sur, Bellavista, Bella Vista, 0823-05404 Panama City, Panama
• View on map
  • Total Relaxation
  • City Style
  • Romantic Break
4 Baths 888.02 ft²

More Great Places to Stay in Panama City:

Best Luxury Hotels that guests love in Panama City

boutique hotels in Panama City
Riu Plaza Panamá
Calle 50 con 53 Este, Marbella, Bella Vista, 0000 Panama City, Panama
8.7
8832 reviews
From $146

Guest Review: In the financial district and lots of friendly people

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boutique hotels in Panama City
Central Hotel Panama Casco Viejo
Casco Antiguo, Avenida Central calle 5ta, Panama City, Panama
8.3
1675 reviews
From $217

Guest Review: staff is so friendly and professional The location is wonderful The breakfast is amazing in the breakfast area they is one waiter, on the heavy side of Weight, I apologize not to remember his name, every morning he greeted me with the biggest smile, always made sure I had coffee double checked on me and Maria. His service is what makes great hotels great. He has black hair, and always wear a black outfit. I just can’t remember his name 😢 Professionals like him that make you wanna come back to the hotel time in and time out. Thank you so much for hiring such a wonderful man 🙏🙏🙏

boutique hotels in Panama City
Marriott Panama Hotel - Albrook
Albrook Mall, Roosevelt Avenue, Panama City, Panama
8.8
1387 reviews
From $197

Guest Review: Convenient, very helpful staff, excellent food in restaurant.

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Frequently Asked Questions

Some of the top luxury hotels in Panama City include Sofitel Legend Casco Viejo, Panama City, known for its stunning views and elegant design, and The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City, which boasts a world-class golf course and lavish amenities.

For a romantic getaway, consider Hotel La Compania, In The Unbound Collection By Hyatt with its historic charm and intimate ambiance, or Waldorf Astoria Panama, which offers luxurious rooms and a rooftop pool perfect for sunset views together.

Food enthusiasts will love American Trade Hotel, which features local culinary experiences, and Bristol Panama, a Registry Collection Hotel, where you can savor exquisite fine dining options created by top chefs.

Families will feel right at home at JW Marriott Panama, offering spacious accommodations and kid-friendly amenities, as well as Hilton Panama, which has a fantastic pool area and family packages for a memorable stay.

For breathtaking views, check out The Westin Panama with its panoramic vistas and beautiful surroundings, or Megapolis Hotel Panama, where you can enjoy stunning skyline views from your room or the rooftop bar.

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